Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | S100A4 | P26447 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29188677 | 0.98 | TDP1 (0.62) | TDP1ALDH1A1CYP3A4MEN1POLB | |
| SCHEMBL5785580 | 0.94 | TDP1 (0.58) | TDP1ALDH1A1CYP3A4MEN1POLB | |
| 4-Bromoaniline SCHEMBL10424963 | 0.93 | ALDH1A1 (0.67) | TDP1ALDH1A1CYP3A4MEN1POLB | |
| SCHEMBL29277905 | 0.84 | MAPT (0.47) | TDP1ALDH1A1CYP3A4MEN1POLB | |
| SCHEMBL990027 | 0.83 | TDP1 (0.64) | TDP1ALDH1A1CYP3A4MEN1POLB | |
| Methane SCHEMBL21383687 | 0.82 | TDP1 (0.62) | TDP1ALDH1A1CYP3A4MEN1POLB | |
| SCHEMBL9293214 | 0.81 | MAPT (0.71) | TDP1ALDH1A1CYP3A4MEN1POLB | |
| SCHEMBL1561802 | 0.80 | TSHR (0.56) | TDP1ALDH1A1CYP3A4MAPTTSHR | |
| SCHEMBL9808956 | 0.79 | TDP1 (0.50) | TDP1ALDH1A1CYP3A4MEN1POLB | |
| SCHEMBL10808103 | 0.79 | LMNA (0.64) | TDP1ALDH1A1CYP3A4MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1627 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118745093-B | Mining modified cement paste composite additive and preparation method and application thereof | 应急管理部信息研究院 | 2025-03-04 | — | — | CN | claimed |
| CN-118993611-B | Accelerator for reducing rebound of sprayed concrete and preparation method thereof | 辽宁鹏硕科技有限公司 | 2025-02-25 | — | — | CN | claimed |
| CN-118993611-A | Accelerator for reducing rebound of sprayed concrete and preparation method thereof | 辽宁鹏硕科技有限公司 | 2024-11-22 | — | — | CN | claimed |
| CN-118745093-A | Mining modified cement paste composite additive and preparation method and application thereof | 应急管理部信息研究院 | 2024-10-08 | — | — | CN | claimed |
| CN-116253686-B | Aminobenzimidazole benzamide derivative and application thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2023-11-17 | — | — | CN | claimed |
| CN-116253686-A | Aminobenzimidazole benzamide derivative and application thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2023-06-13 | — | — | CN | claimed |
| CN-115433092-A | Synthesis process of 4-bromo o-phenylenediamine | 苏州信礼发医药技术有限公司 | 2022-12-06 | — | — | CN | claimed |
| CN-115417771-A | Preparation method of 2-nitro-4-bromobenzaldehyde | 无锡双启科技有限公司 | 2022-12-02 | — | — | CN | claimed |
| CN-113968844-A | Novel method for synthesizing 7-bromo-2- (1-methyl-1H-pyrazol-4-yl) quinoxaline | 苏州匠化生物科技有限公司 | 2022-01-25 | — | — | CN | claimed |
| CN-112778793-A | Pyridone dispersed orange yellow dye composition and fabric dyeing process thereof | 邓生平 | 2021-05-11 | — | — | CN | claimed |
| CN-110655505-A | 6- (2-amino-1H-benzo [ d ] imidazol-6-yl) quinazolin-4 (3H) -ones | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2020-01-07 | — | — | CN | claimed |
| CN-108774138-A | Preparation method of 4-bromine o-phenylenediamine | 海门市新港医药科技有限公司 | 2018-11-09 | — | — | CN | claimed |
| CN-108727276-A | Benzimidazole derivatives and their preparation | 江苏理工学院 | 2018-11-02 | — | — | CN | claimed |
| CN-108689945-A | Preparation method of benzimidazole derivative | 江苏理工学院 | 2018-10-23 | — | — | CN | claimed |
| CN-105399683-B | Benzimidazole derivatives and process for preparing the same | 江苏理工学院 | 2018-07-20 | — | — | CN | claimed |
| US-20120053188-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE OF HYDROXAMIC ACID DERIVATIVES | THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE(TGEN (US) | 2012-03-01 | — | — | US | claimed |
| WO-2009100045-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE OF HYDROXAMIC ACID DERIVATIVES | TRANSLATIONAL GENOMICS RESEARCH INSTITUTE (US) | 2009-08-13 | — | — | WO | claimed |
| US-5891199-A | CONDENSATION PRODUCT OF A CHITOSAN WITH A HALOGEN-SUBSTITUTED NITROANILINE COMPOUND. | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (KGAA) (DE) | 1999-04-06 | — | — | US | claimed |
| EP-0182330-B1 | USE OF 2-NITROANILINE DERIVATIVES AS HAIR DYEING AGENTS, AND 2-NITROANILINE DERIVATIVES | Wella Aktiengesellschaft (DE) | 1991-05-15 | — | — | EP | claimed |
| EP-0182330-A2 | Use of 2-nitroaniline derivatives as hair dyeing agents, and 2-nitroaniline derivatives | Wella Aktiengesellschaft (DE) | 1986-05-28 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053188-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE OF HYDROXAMIC ACID DERIVATIVES | HDAC5, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, HDAC4 | TDP1 3005/4885ALDH1A1 863/4885CYP3A4 1165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.