Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | S100A4 | P26447 | 1/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.53 |
| ▸ | CASP6 | P55212 | 1/20 | 0.50 |
| ▸ | ERN1 | O75460 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL204357 | 0.84 | S100A4 (0.61) | TSHRCYP3A4S100A4TRPV1ERN1 | |
| SCHEMBL29395434 | 0.84 | S100A4 (0.56) | CYP3A4S100A4TRPV1ERN1MAPK1 | |
| SCHEMBL24508 | 0.84 | S100A4 (0.56) | CYP3A4S100A4TRPV1ERN1MAPK1 | |
| SCHEMBL26205134 | 0.84 | S100A4 (0.56) | TSHRCYP3A4S100A4TRPV1CASP6 | |
| SCHEMBL29431838 | 0.84 | CYP19A1 (0.49) | TSHRCYP3A4S100A4TRPV1TDP1 | |
| SCHEMBL165733 | 0.84 | CYP19A1 (0.49) | TSHRCYP3A4S100A4TRPV1TDP1 | |
| SCHEMBL3282011 | 0.82 | S100A4 (0.50) | TSHRCYP3A4S100A4TRPV1ERN1 | |
| SCHEMBL405513 | 0.80 | PARP1 (0.53) | TSHRCYP3A4S100A4TRPV1ERN1 | |
| SCHEMBL15749845 | 0.80 | S100A4 (0.45) | TSHRCYP3A4S100A4TRPV1CASP6 | |
| SCHEMBL16655574 | 0.80 | S100A4 (0.49) | TSHRCYP3A4S100A4TRPV1ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112939829-B | Synthetic method of aryl trifluoromethyl thioether | 武汉药明康德新药开发有限公司 | 2023-02-21 | — | — | CN | claimed |
| CN-112939829-A | Synthetic method of aryl trifluoromethyl thioether | 武汉药明康德新药开发有限公司 | 2021-06-11 | — | — | CN | claimed |
| CN-116023237-B | Continuous preparation method of hydroquinone in water phase | 复旦大学 | 2024-09-06 | — | — | CN | disclosed |
| CN-116574037-A | Continuous synthesis method of calcium dobesilate | 宁夏元康药业有限公司 | 2023-08-11 | — | — | CN | disclosed |
| US-20230212158-A1 | SMALL MOLECULE INHIBITORS OF GALECTIN-3 | BRISTOL MYERS SQUIBB CO (US) | 2023-07-06 | — | — | US | disclosed |
| CN-116023237-A | Continuous preparation method of hydroquinone in water phase | 复旦大学 | 2023-04-28 | — | — | CN | disclosed |
| WO-2023048034-A1 | METHOD FOR PRODUCING AROMATIC COMPOUND HAVING ETHYNYL GROUP | 東レ・ファインケミカル株式会社 | 2023-03-30 | — | — | WO | disclosed |
| CN-112939829-B | Synthetic method of aryl trifluoromethyl thioether | 武汉药明康德新药开发有限公司 | 2023-02-21 | — | — | CN | disclosed |
| EP-2170912-B3 | NEW PHOSPHORUS CONTAINING HETEROCYCLIC COMPOUNDS, SUGAR ANALOGUES, AND COMPOSITIONS HAVING ANTI-CANCER ACTIVITY CONTAINING THE SAME | CENTRE NAT RECH SCIENT (FR) | 2022-06-15 | — | — | EP | disclosed |
| CN-112939829-A | Synthetic method of aryl trifluoromethyl thioether | 武汉药明康德新药开发有限公司 | 2021-06-11 | — | — | CN | disclosed |
| CN-108727394-A | A kind of bipolarity main body electroluminescent organic material and its application | 中节能万润股份有限公司 | 2018-11-02 | — | — | CN | disclosed |
| EP-0341496-B1 | Modified diene polymer rubbers | SUMITOMO CHEMICAL CO (JP) | 1993-10-20 | — | — | EP | disclosed |
| US-5219938-A | Reacting a living polymer of a conjugated diene with a tin or silicon compound and with a nitro compound, a phosphoryl chloride, aminosilane, an acrylamide or an aminovinylsilane; auto tires; impact strength; cold resistance; storage | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-06-15 | — | — | US | disclosed |
| US-5128416-A | Automobile tire treads | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-07-07 | — | — | US | disclosed |
| US-5015692-A | Rubbers for tires having impact strength | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-05-14 | — | — | US | disclosed |
| US-4957976-A | IMPROVED PROPERTIES FOR AUTOMOBILE TIRES, MODIFIED WITH PHOSPHORYL CHLORIDE | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1990-09-18 | — | — | US | disclosed |
| EP-0341496-A2 | Modified diene polymer rubbers | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-11-15 | — | — | EP | disclosed |
| EP-0270071-A2 | Process for preparing modified diene polymer rubbers | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-06-08 | — | — | EP | disclosed |
| US-4520197-A | Tetrahydrobenzodiazaphosphorindiones and tetrahydropyridodiazaphosphorindiones | ZOECON CORPORATION (US) | 1985-05-28 | — | — | US | disclosed |
| US-4433149-A | Esters of ureido-phenyl (or pyridyl) phosphinic acids | ZOECON CORPORATION (US) | 1984-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230212158-A1 | SMALL MOLECULE INHIBITORS OF GALECTIN-3 | LGALS3, LGALS1, LGALS3BP | TSHR 1441/4885CYP3A4 4307/4885S100A4 863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.