Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 6/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | CYP2E1 | P05181 | 4/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.37 |
| ▸ | CYP2B6 | P20813 | 4/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 2/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12097947 | 0.93 | CYP2A6 (0.43) | CYP2A6GABRG2GABRB3GABRA3CYP2E1 | |
| SCHEMBL1870362 | 0.82 | PIK3CB (0.32) | — | |
| SCHEMBL12097774 | 0.72 | PIK3CA (0.45) | GABRG2GABRB3GABRA3CYP11B1CYP11B2 | |
| SCHEMBL1866743 | 0.72 | PIK3CA (0.44) | CYP2A6CYP2E1CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL1869651 | 0.72 | ALDH1A1 (0.40) | CYP2A6GABRG2GABRB3GABRA3FYN | |
| SCHEMBL12097916 | 0.71 | PIK3CA (0.42) | CYP2A6GABRG2GABRB3GABRA3CYP2E1 | |
| SCHEMBL12097911 | 0.71 | FYN (0.37) | CYP2A6CYP2E1CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL1872292 | 0.71 | CYP2A6 (0.43) | CYP2A6GABRG2GABRB3GABRA3CYP2E1 | |
| SCHEMBL12097820 | 0.70 | ALDH1A1 (0.42) | GABRG2GABRB3GABRA3CYP2C19CYP3A4 | |
| SCHEMBL15743311 | 0.70 | CYP2A6 (0.46) | CYP2A6GABRG2GABRB3GABRA3CYP2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120232072-A1 | IMIDAZOPYRIDINE DERIVATIVES | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2012-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120232072-A1 | IMIDAZOPYRIDINE DERIVATIVES | IL6, IL6ST, STAT3 | CYP2A6 1008/4885GABRG2 2990/4885GABRB3 1674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.