Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 7/20 | 0.43 |
| ▸ | CYP2E1 | P05181 | 4/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.43 |
| ▸ | CYP2B6 | P20813 | 4/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | AKT2 | P31751 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.41 |
| ▸ | ERN1 | O75460 | 3/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15743223 | 0.80 | AKT1 (0.43) | CYP2A6CYP2E1CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL12097947 | 0.76 | CYP2A6 (0.43) | CYP2A6CYP2E1CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL1866743 | 0.76 | PIK3CA (0.44) | CYP2A6CYP2E1CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL1871966 | 0.75 | CYP11B1 (0.40) | CYP2A6MKNK1MKNK2GABRG2GABRB3 | |
| SCHEMBL1871967 | 0.75 | CYP11B1 (0.40) | CYP2A6MKNK1MKNK2GABRG2GABRB3 | |
| SCHEMBL1871270 | 0.74 | PIK3CA (0.38) | AKT1AKT2MKNK1MKNK2MC4R | |
| SCHEMBL1869444 | 0.74 | PIK3CA (0.38) | AKT1AKT2MKNK1MKNK2MC4R | |
| SCHEMBL1870516 | 0.73 | PIK3CA (0.40) | AKT1AKT2MKNK1MKNK2 | |
| SCHEMBL1865579 | 0.73 | FLT3 (0.42) | — | |
| SCHEMBL1865829 | 0.72 | L3MBTL1 (0.42) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8741932-B2 | Imidazopyridine derivatives | Piramal Enterprises Limited (IN) | 2014-06-03 | — | — | US | disclosed |
| US-20120232072-A1 | IMIDAZOPYRIDINE DERIVATIVES | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2012-09-13 | — | — | US | disclosed |
| EP-2496577-A1 | IMIDAZOPYRIDINE DERIVATIVES | Piramal Life Sciences Limited (IN) | 2012-09-12 | — | — | EP | disclosed |
| WO-2011055320-A1 | IMIDAZOPYRIDINE DERIVATIVES | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2011-05-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120232072-A1 | IMIDAZOPYRIDINE DERIVATIVES | IL6, IL6ST, STAT3 | CYP2A6 1008/4885CYP2E1 1471/4885CYP2C9 2209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.