Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.42 |
| ▸ | USP2 | O75604 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2142828 | 0.81 | HPGD (0.55) | ACACBHPGDMAPK1SCD5USP2 | |
| SCHEMBL20411482 | 0.76 | MGLL (0.65) | ACACBSCD5MEN1KMT2ATSHR | |
| SCHEMBL16678850 | 0.75 | USP2 (0.49) | ACACBHPGDSCD5CYP3A4USP2 | |
| SCHEMBL15171024 | 0.74 | SPR (0.61) | SCD5CYP3A4CYP11B2 | |
| SCHEMBL23906185 | 0.73 | CYP11B2 (0.52) | ACACBHPGDSCD5USP2CYP11B2 | |
| SCHEMBL25275679 | 0.73 | CYP11B2 (0.52) | ACACBHPGDSCD5USP2CYP11B2 | |
| SCHEMBL25052826 | 0.73 | HPGD (0.46) | ACACBHPGDSCD5MEN1KMT2A | |
| SCHEMBL14240265 | 0.73 | HPGD (0.46) | ACACBHPGDSCD5MEN1KMT2A | |
| SCHEMBL24112531 | 0.72 | CYP11B2 (0.51) | ACACBHPGDSCD5USP2CYP11B2 | |
| SCHEMBL18390388 | 0.71 | USP2 (0.50) | ACACBHPGDSCD5CYP3A4USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2242759-B1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2012-09-12 | — | — | EP | disclosed |