Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12708609 | 0.95 | NPSR1 (0.66) | NPSR1KMT2AMEN1SMN1; SMN2BCHE | |
| SCHEMBL13681670 | 0.92 | NPSR1 (0.52) | NPSR1KMT2AMEN1SMN1; SMN2BCHE | |
| SCHEMBL19764243 | 0.84 | GNAI3 (0.49) | NPSR1KMT2AMEN1BCHEACHE | |
| SCHEMBL13681678 | 0.84 | NPSR1 (0.45) | NPSR1KMT2AMEN1BCHEACHE | |
| SCHEMBL20061878 | 0.83 | LMNA (0.44) | NPSR1KMT2AMEN1ALDH1A1 | |
| SCHEMBL22332304 | 0.82 | ALDH1A1 (0.46) | NPSR1KMT2AALDH1A1 | |
| SCHEMBL20061880 | 0.80 | EPHX1 (0.51) | NPSR1KMT2AMEN1ALDH1A1EPHX1 | |
| SCHEMBL20061877 | 0.80 | KDM4E (0.45) | NPSR1KMT2AMEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL22332321 | 0.79 | NPSR1 (0.41) | NPSR1KMT2AMEN1L3MBTL1HPGD | |
| SCHEMBL25045633 | 0.79 | NPSR1 (0.39) | NPSR1KMT2AMEN1HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888082-B1 | MOTILIDE COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2012-09-12 | — | — | EP | disclosed |
| US-7582611-B2 | Treating disorders of gastric motility; decreasing side effects of erythromycin A | PFIZER INC. (US) | 2009-09-01 | — | — | US | disclosed |