Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.46 |
| ▸ | RAB9A | P51151 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14319141 | 0.86 | NPC1 (0.48) | NPC1RAB9AKMT2AALDH1A1MEN1 | |
| SCHEMBL1464756 | 0.79 | NPC1 (0.46) | NPC1RAB9AKMT2AALDH1A1MEN1 | |
| SCHEMBL12102188 | 0.76 | ACVR1 (0.47) | KMT2AMEN1 | |
| SCHEMBL1465302 | 0.75 | CNR2 (0.52) | NPC1RAB9AKMT2AALDH1A1MEN1 | |
| SCHEMBL13842705 | 0.74 | ATAD2 (0.48) | NPC1RAB9AKMT2AALDH1A1MEN1 | |
| SCHEMBL14309230 | 0.73 | NPC1 (0.47) | NPC1RAB9AKMT2AALDH1A1MEN1 | |
| SCHEMBL2893355 | 0.73 | NR3C1 (0.52) | NPC1RAB9AKMT2AALDH1A1MEN1 | |
| SCHEMBL77451 | 0.73 | ATAD2 (0.61) | NPC1RAB9AKMT2AALDH1A1MEN1 | |
| SCHEMBL14222564 | 0.72 | ATAD2 (0.46) | NPC1RAB9AKMT2AALDH1A1MEN1 | |
| SCHEMBL15219074 | 0.72 | ATAD2 (0.46) | NPC1RAB9AKMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081905-B1 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INT (DE) | 2012-09-12 | — | — | EP | disclosed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | disclosed |