Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 12/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1464615 | 0.87 | SLC22A12 (0.65) | SLC22A12PPARA | |
| SCHEMBL1464264 | 0.80 | SLC22A12 (0.47) | SLC22A12PPARAKMT2AGPR119MEN1 | |
| SCHEMBL1464605 | 0.73 | RAB9A (0.47) | SLC22A12KMT2AMEN1 | |
| SCHEMBL1464556 | 0.72 | CNR2 (0.43) | SLC22A12 | |
| SCHEMBL1464366 | 0.72 | SLC22A12 (0.42) | SLC22A12KMT2AMEN1 | |
| SCHEMBL1464739 | 0.72 | CNR1 (0.46) | SLC22A12 | |
| SCHEMBL30846771 | 0.71 | KMT2A (0.44) | SLC22A12KMT2AMEN1 | |
| SCHEMBL4032639 | 0.71 | KMT2A (0.44) | SLC22A12KMT2AMEN1 | |
| SCHEMBL27112680 | 0.71 | SLC22A12 (0.39) | SLC22A12GPR119 | |
| SCHEMBL30686452 | 0.70 | KIF11 (0.38) | SLC22A12KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081905-B1 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INT (DE) | 2012-09-12 | — | — | EP | disclosed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | disclosed |