Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | EGLN2 | Q96KS0 | 4/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.34 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27117919 | 1.00 | KIF11 (0.38) | KIF11AREGLN2SLC22A12CYP11B1 | |
| SCHEMBL4032639 | 0.83 | KMT2A (0.44) | KIF11AREGLN2SLC22A12CYP11B1 | |
| SCHEMBL30846771 | 0.83 | KMT2A (0.44) | KIF11AREGLN2SLC22A12CYP11B1 | |
| SCHEMBL29416796 | 0.77 | EGLN2 (0.44) | KIF11EGLN2CYP11B1CYP11B2CYP2A6 | |
| SCHEMBL229147 | 0.77 | EGLN2 (0.44) | KIF11EGLN2CYP11B1CYP11B2CYP2A6 | |
| SCHEMBL27112680 | 0.76 | SLC22A12 (0.39) | KIF11ARSLC22A12CYP2A6MAOA | |
| SCHEMBL8111127 | 0.76 | CA2 (0.51) | ARSLC22A12CA2MAOAMAOB | |
| SCHEMBL6517303 | 0.74 | CA12 (0.44) | ARCYP2A6ALDH1A1CA12CA2 | |
| SCHEMBL6516138 | 0.74 | SLC6A2 (0.49) | AREGLN2CYP2A6ALDH1A1CA12 | |
| SCHEMBL7897191 | 0.74 | MAOB (0.57) | EGLN2ALDH1A1MAOAMAOBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117242067-B | Novel aryl ether substituted heterocycles as GLP1R agonists | 杭州德睿智药科技有限公司 | 2025-03-25 | — | — | CN | disclosed |
| CN-117242067-A | Novel aryl ether substituted heterocycles as GLP1R agonists | 杭州德睿智药科技有限公司 | 2023-12-15 | — | — | CN | disclosed |