Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 20/20 | 0.56 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12102825 | 0.92 | S1PR1 (0.58) | S1PR1S1PR3CYP2C9 | |
| SCHEMBL1293239 | 0.88 | S1PR1 (0.55) | S1PR1S1PR3CYP2C9 | |
| SCHEMBL2587686 | 0.85 | S1PR1 (0.60) | S1PR1S1PR3CYP2C9 | |
| SCHEMBL12176514 | 0.85 | S1PR1 (0.43) | S1PR1S1PR3CYP2C9 | |
| SCHEMBL1293498 | 0.85 | S1PR1 (0.52) | S1PR1S1PR3CYP2C9 | |
| SCHEMBL1293076 | 0.82 | S1PR1 (0.49) | S1PR1S1PR3CYP2C9 | |
| SCHEMBL1293077 | 0.82 | S1PR1 (0.49) | S1PR1S1PR3CYP2C9 | |
| SCHEMBL1293335 | 0.81 | S1PR1 (0.77) | S1PR1S1PR3CYP2C9 | |
| SCHEMBL1293152 | 0.80 | S1PR1 (0.77) | S1PR1S1PR3CYP2C9 | |
| SCHEMBL1293287 | 0.79 | S1PR1 (0.67) | S1PR1S1PR3CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389508-B2 | Heterocyclic compounds | GLAXO GROUP LIMITED (GB) | 2013-03-05 | — | — | US | disclosed |
| US-8389508-B2 | Heterocyclic compounds | GLAXO GROUP LIMITED (GB) | 2013-03-05 | — | — | US | disclosed |
| US-20110269738-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2011-11-03 | — | — | US | disclosed |
| US-20110269738-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2011-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269738-A1 | COMPOUNDS | CYP11B2, CYP11B1, GPR119 | S1PR1 1075/4885S1PR3 1079/4885CYP2C9 598/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.