SCHEMBL12108331

SCHEMBL12108331

CN1C(=O)c2ccc3c4c(-c5ccccc5)cc5c6c(ccc(c7c(-c8ccccc8)cc(c2c37)C1=O)c64)C(=O)N(C)C5=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
USP2 O75604 2/20 0.43
KEAP1 Q14145 2/20 0.43
NFE2L2 Q16236 2/20 0.43
HPGD P15428 2/20 0.43
ATM Q13315 1/20 0.43
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 1/20 0.43
APP P05067 1/20 0.42
POLB P06746 1/20 0.41
PRMT1 Q99873 1/20 0.41
HSD17B10 Q99714 1/20 0.40
CASP3 P42574 1/20 0.40
BRD4 O60885 2/20 0.39
MAOA P21397 1/20 0.39
TERT O14746 3/20 0.39
RET P07949 1/20 0.37
NR1H2 P55055 1/20 0.36
NR1H3 Q13133 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12108335 0.86 APP (0.45) MEN1KMT2AUSP2KEAP1NFE2L2
SCHEMBL25582847 0.84 TERT (0.47) MEN1KMT2AUSP2ATMKDM4E
SCHEMBL25582844 0.84 CYP1B1 (0.47) MEN1KMT2AUSP2KEAP1NFE2L2
SCHEMBL12108267 0.82 TERT (0.41) MEN1KMT2AUSP2KEAP1NFE2L2
SCHEMBL25582856 0.82 MEN1 (0.47) MEN1KMT2AUSP2ATMKDM4E
SCHEMBL25582862 0.81 ALDH1A1 (0.44) MEN1KMT2AKEAP1NFE2L2HPGD
SCHEMBL25582868 0.80 TERT (0.34) MEN1KMT2AALDH1A1HSD17B10BRD4
SCHEMBL12108169 0.80 PGR (0.46) MEN1KMT2AUSP2KEAP1NFE2L2
SCHEMBL12449217 0.79 MEN1 (0.44) MEN1KMT2AUSP2KEAP1NFE2L2
SCHEMBL25582864 0.79 TDP1 (0.40) MEN1KMT2AUSP2KDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230180605-A1 ORGANIC PHOTODETECTOR AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-08 US disclosed
US-20230180605-A1 ORGANIC PHOTODETECTOR AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-08 US disclosed
US-8465889-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2013-06-18 US disclosed
US-8465889-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2013-06-18 US disclosed
US-8435706-B2 2013-05-07 US disclosed
US-8435706-B2 2013-05-07 US disclosed
US-20110268472-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2011-11-03 US disclosed
US-20110268472-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2011-11-03 US disclosed