SCHEMBL12109752

SCHEMBL12109752

Cc1ccc2c3c(ccc(C)c13)C(=O)C2=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP2 O95551 2/20 0.54
NSD2 O96028 1/20 0.54
HSP90AA1 P07900 1/20 0.54
PAX8 Q06710 1/20 0.54
SMN1; SMN2 Q16637 3/20 0.45
KDM4E B2RXH2 3/20 0.45
MAPT P10636 2/20 0.45
PABPC1 P11940 1/20 0.45
BCHE P06276 3/20 0.43
CES1 P23141 3/20 0.43
ACHE P22303 1/20 0.43
ALDH1A1 P00352 3/20 0.40
CES2 O00748 2/20 0.40
MCL1 Q07820 1/20 0.40
ELANE P08246 4/20 0.38
NPC1 O15118 2/20 0.38
MAPK1 P28482 2/20 0.38
RAB9A P51151 2/20 0.38
CYP3A4 P08684 2/20 0.38
TSHR P16473 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3198619 0.82 CES1 (0.55) TDP2NSD2HSP90AA1PAX8SMN1; SMN2
SCHEMBL12109775 0.80 TDP2 (0.47) TDP2NSD2HSP90AA1PAX8SMN1; SMN2
SCHEMBL4612945 0.78 CES1 (0.59) TDP2NSD2HSP90AA1PAX8SMN1; SMN2
SCHEMBL13009495 0.77 TYMS (0.48) TDP2NSD2HSP90AA1PAX8SMN1; SMN2
SCHEMBL31001032 0.74 CYP1A2 (0.44) TDP2NSD2HSP90AA1PAX8KDM4E
SCHEMBL597313 0.74 CYP1A2 (0.44) TDP2NSD2HSP90AA1PAX8KDM4E
SCHEMBL12293691 0.74 MAPT (0.79) TDP2NSD2HSP90AA1PAX8SMN1; SMN2
SCHEMBL14135639 0.73 SMN1; SMN2 (0.64) TDP2SMN1; SMN2KDM4EMAPTPABPC1
SCHEMBL12109848 0.72 TDP2 (0.39) TDP2NSD2HSP90AA1PAX8SMN1; SMN2
SCHEMBL12109880 0.72 TDP2 (0.39) TDP2NSD2HSP90AA1PAX8SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109956979-B Heat-resistant asymmetric alpha-diimine nickel olefin catalyst and preparation method and application thereof 杭州星庐科技有限公司 2023-04-07 CN disclosed
CN-109956979-B Heat-resistant asymmetric alpha-diimine nickel olefin catalyst and preparation method and application thereof 杭州星庐科技有限公司 2023-04-07 CN disclosed
CN-108864343-B Binuclear (alpha-diimine) nickel/palladium olefin catalyst, preparation and application 浙江大学 2021-01-05 CN disclosed
CN-108864342-B Binuclear (alpha-diimine) nickel/palladium olefin catalyst and preparation and application thereof 浙江大学 2020-10-09 CN disclosed
CN-109956979-A Heat-resisting asymmetry alpha-diimine nickel alkene catalyst and its preparation method and application 杭州星庐科技有限公司 2019-07-02 CN disclosed
CN-109956979-A Heat-resisting asymmetry alpha-diimine nickel alkene catalyst and its preparation method and application 杭州星庐科技有限公司 2019-07-02 CN disclosed
CN-107011365-A Thiadiazoles system compound, light-emitting component compound, light-emitting component, light-emitting device, authentication device and electronic equipment 精工爱普生株式会社 2017-08-04 CN disclosed
US-9722184-B2 Thiadiazole, compound for light-emitting elements, light-emitting element, light-emitting apparatus, authentication apparatus, and electronic device SEIKO EPSON CORPORATION (JP) 2017-08-01 US disclosed
US-9722184-B2 Thiadiazole, compound for light-emitting elements, light-emitting element, light-emitting apparatus, authentication apparatus, and electronic device SEIKO EPSON CORPORATION (JP) 2017-08-01 US disclosed
US-9722184-B2 Thiadiazole, compound for light-emitting elements, light-emitting element, light-emitting apparatus, authentication apparatus, and electronic device SEIKO EPSON CORPORATION (JP) 2017-08-01 US disclosed
US-20140110686-A1 THIADIAZOLE, COMPOUND FOR LIGHT-EMITTING ELEMENTS, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING APPARATUS, AUTHENTICATION APPARATUS, AND ELECTRONIC DEVICE SEIKO EPSON CORPORATION (JP) 2014-04-24 US disclosed
US-20140110686-A1 THIADIAZOLE, COMPOUND FOR LIGHT-EMITTING ELEMENTS, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING APPARATUS, AUTHENTICATION APPARATUS, AND ELECTRONIC DEVICE SEIKO EPSON CORPORATION (JP) 2014-04-24 US disclosed
US-20140110686-A1 THIADIAZOLE, COMPOUND FOR LIGHT-EMITTING ELEMENTS, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING APPARATUS, AUTHENTICATION APPARATUS, AND ELECTRONIC DEVICE SEIKO EPSON CORPORATION (JP) 2014-04-24 US disclosed
US-8465889-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2013-06-18 US disclosed
US-8435706-B2 2013-05-07 US disclosed
US-20110268472-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2011-11-03 US disclosed
US-20110268472-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2011-11-03 US disclosed
US-7888452-B2 Low band gap semiconducting polymers NDSU RESEARCH FOUNDATION (US) 2011-02-15 US disclosed
WO-2010087520-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2010-08-05 WO disclosed
US-20090065059-A1 LOW BAND GAP SEMICONDUCTING POLYMERS NDSU RESEARCH FOUNDATION (US) 2009-03-12 US disclosed