Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 5/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL148025 | 0.84 | TYMS (0.62) | TYMSALOX15TDP1MEN1POLB | |
| SCHEMBL6391690 | 0.80 | SNCA (0.37) | TYMSALOX15TDP1TDP2NSD2 | |
| SCHEMBL6984126 | 0.79 | MAPT (0.62) | TYMSALOX15TDP1MEN1POLB | |
| SCHEMBL11947506 | 0.78 | MAPT (0.49) | TYMSALOX15TDP1MEN1POLB | |
| SCHEMBL14003684 | 0.78 | MAPT (0.49) | TYMSALOX15TDP1MEN1POLB | |
| SCHEMBL12109752 | 0.77 | TDP2 (0.54) | TDP2NSD2HSP90AA1PAX8MEN1 | |
| SCHEMBL16847280 | 0.76 | TYMS (0.56) | TYMSTDP1POLBKDM4ECYP1A2 | |
| SCHEMBL2607526 | 0.76 | TYMS (0.41) | TYMSALOX15TDP1MEN1POLB | |
| SCHEMBL15119575 | 0.75 | TDP1 (0.65) | TYMSALOX15TDP1TDP2MEN1 | |
| SCHEMBL31185814 | 0.75 | TYMS (0.52) | TYMSALOX15TDP1MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020203514-A1 | COLORING COMPOSITION, COMPOUND, COLOR FILTER, AND DISPLAY DEVICE | 住友化学株式会社 | 2020-10-08 | — | — | WO | disclosed |
| US-9790423-B2 | Cyanated naphthalenebenzimidazole compounds | BASF SE (DE) | 2017-10-17 | — | — | US | disclosed |
| US-20160177177-A1 | CYANATED NAPHTHALENEBENZIMIDAZOLE COMPOUNDS | BASF SE (DE) | 2016-06-23 | — | — | US | disclosed |
| US-8894881-B2 | 1,8-naphthalimide derivatives as scintillation agents, in particular for discriminating between fast neutrons and gamma rays | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2014-11-25 | — | — | US | disclosed |
| US-20100314556-A1 | 1,8-NAPHTHALIMIDE DERIVATIVES AS SCINTILLATION AGENTS, IN PARTICULAR FOR DISCRIMINATING BETWEEN FAST NEUTRONS AND GAMMA RAYS | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2010-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100314556-A1 | 1,8-NAPHTHALIMIDE DERIVATIVES AS SCINTILLATION AGENTS, IN PARTICULAR FOR DISCRIMINATING BETWEEN FAST NEUTRONS AND GAMMA RAYS | NPM1, NDC1, KPNB1 | TYMS 490/4885ALOX15 4816/4885TDP1 311/4885 |
| US-20160177177-A1 | CYANATED NAPHTHALENEBENZIMIDAZOLE COMPOUNDS | RB1, RARB, RARA | TYMS 4324/4885ALOX15 4653/4885TDP1 2520/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.