Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 5/20 | 0.59 |
| ▸ | BCHE | P06276 | 3/20 | 0.59 |
| ▸ | ACHE | P22303 | 1/20 | 0.59 |
| ▸ | CES2 | O00748 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | S100A4 | P26447 | 6/20 | 0.44 |
| ▸ | PTPRC | P08575 | 5/20 | 0.44 |
| ▸ | TDP2 | O95551 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | PLCG1 | P19174 | 3/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | APAF1 | O14727 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3198619 | 0.96 | CES1 (0.55) | CES1BCHEACHECES2ALDH1A1 | |
| SCHEMBL4612585 | 0.87 | BCL2 (0.54) | CES1BCHEACHECES2ALDH1A1 | |
| SCHEMBL3187376 | 0.81 | S100A4 (0.46) | CES1BCHEACHECES2ALDH1A1 | |
| SCHEMBL11428765 | 0.78 | S100A4 (0.44) | CES1BCHEACHECES2ALDH1A1 | |
| SCHEMBL12109752 | 0.78 | TDP2 (0.54) | CES1BCHEACHECES2ALDH1A1 | |
| SCHEMBL2699746 | 0.77 | BCHE (1.00) | CES1BCHEACHEALDH1A1S100A4 | |
| SCHEMBL14257723 | 0.76 | LMNA (0.50) | CES1BCHEACHECES2ALDH1A1 | |
| SCHEMBL10048344 | 0.76 | CES1 (0.48) | CES1BCHEACHECES2ALDH1A1 | |
| SCHEMBL12941544 | 0.74 | BCHE (0.40) | CES1BCHEACHECES2ALDH1A1 | |
| SCHEMBL16601741 | 0.73 | BCHE (0.39) | CES1BCHEACHECES2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1502580-B1 | Use in dyeing of aromatic polycyclic vicinal triones with condensed cycles | OREAL (FR) | 2008-01-23 | — | — | EP | claimed |
| US-7179304-B2 | Process for dyeing keratin fibers with at least one polycyclic aromatic vicinal trione | L'OREAL S.A. (FR) | 2007-02-20 | — | — | US | claimed |
| US-20050050652-A1 | Process for dyeing keratin fibers with at least one polycyclic aromatic vicinal trione | L'OREAL S.A. (FR) | 2005-03-10 | — | — | US | claimed |
| EP-1502580-A1 | Use in dyeing of aromatic polycyclic vicinal triones with condensed cycles | L'OREAL (FR) | 2005-02-02 | — | — | EP | claimed |
| EP-2259371-B1 | ELECTRODE ACTIVE MATERIAL FOR ELECTRICITY STORAGE DEVICE, ELECTRICITY STORAGE DEVICE, ELECTRONIC DEVICE AND TRANSPORT DEVICE | PANASONIC CORP (JP) | 2015-04-01 | — | — | EP | disclosed |
| US-8338028-B2 | Electrode active material for power storage device, power storage device, and electronic and transport devices | PANASONIC CORPORATION (JP) | 2012-12-25 | — | — | US | disclosed |
| US-8338028-B2 | Electrode active material for power storage device, power storage device, and electronic and transport devices | PANASONIC CORPORATION (JP) | 2012-12-25 | — | — | US | disclosed |
| EP-2259371-A1 | ELECTRODE ACTIVE MATERIAL FOR ELECTRICITY STORAGE DEVICE, ELECTRICITY STORAGE DEVICE, ELECTRONIC DEVICE AND TRANSPORT DEVICE | Panasonic Corporation (JP) | 2010-12-08 | — | — | EP | disclosed |
| US-20100196758-A1 | ELECTRODE ACTIVE MATERIAL FOR POWER STORAGE DEVICE, POWER STORAGE DEVICE, AND ELCTRONIC AND TRANSPORT DEVICES | PANASONIC CORPORATION (JP) | 2010-08-05 | — | — | US | disclosed |
| US-20100196758-A1 | ELECTRODE ACTIVE MATERIAL FOR POWER STORAGE DEVICE, POWER STORAGE DEVICE, AND ELCTRONIC AND TRANSPORT DEVICES | PANASONIC CORPORATION (JP) | 2010-08-05 | — | — | US | disclosed |
| WO-2009118990-A1 | ELECTRODE ACTIVE MATERIAL FOR ELECTRICITY STORAGE DEVICE, ELECTRICITY STORAGE DEVICE, ELECTRONIC DEVICE AND TRANSPORT DEVICE | パナソニック株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |
| EP-1502580-B1 | Use in dyeing of aromatic polycyclic vicinal triones with condensed cycles | OREAL (FR) | 2008-01-23 | — | — | EP | disclosed |
| US-7179304-B2 | Process for dyeing keratin fibers with at least one polycyclic aromatic vicinal trione | L'OREAL S.A. (FR) | 2007-02-20 | — | — | US | disclosed |
| US-7179304-B2 | Process for dyeing keratin fibers with at least one polycyclic aromatic vicinal trione | L'OREAL S.A. (FR) | 2007-02-20 | — | — | US | disclosed |
| US-7179304-B2 | Process for dyeing keratin fibers with at least one polycyclic aromatic vicinal trione | L'OREAL S.A. (FR) | 2007-02-20 | — | — | US | disclosed |
| US-20050050652-A1 | Process for dyeing keratin fibers with at least one polycyclic aromatic vicinal trione | L'OREAL S.A. (FR) | 2005-03-10 | — | — | US | disclosed |
| EP-1502580-A1 | Use in dyeing of aromatic polycyclic vicinal triones with condensed cycles | L'OREAL (FR) | 2005-02-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050050652-A1 | Process for dyeing keratin fibers with at least one polycyclic aromatic vicinal trione | KRT18, HKDC1, JUP | CES1 3784/4885BCHE 2037/4885ACHE 1234/4885 |
| US-20100196758-A1 | ELECTRODE ACTIVE MATERIAL FOR POWER STORAGE DEVICE, POWER STORAGE DEVICE, AND ELCTRONIC AND TRANSPORT DEVICES | CXCR5, CX3CR1, CCR7 | CES1 2440/4885BCHE 1857/4885ACHE 2726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.