Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12112475 | 0.91 | TSHR (0.47) | KITTSHRKDM4EALDH1A1HSD17B10 | |
| SCHEMBL12848600 | 0.91 | TSHR (0.51) | KITTSHRKDM4EALDH1A1HSD17B10 | |
| SCHEMBL12111320 | 0.88 | MRGPRX4 (0.47) | MAPTSMN1; SMN2MEN1KMT2AL3MBTL1 | |
| SCHEMBL12112494 | 0.88 | KIT (0.43) | KITTSHRPDE4BMAPTNPC1 | |
| SCHEMBL15374943 | 0.86 | TSHR (0.47) | TSHRKDM4EALDH1A1HSD17B10USP2 | |
| SCHEMBL12112729 | 0.86 | TSHR (0.48) | TSHRKDM4EALDH1A1HSD17B10USP2 | |
| SCHEMBL12112565 | 0.85 | KDM4E (0.47) | KITTSHRKDM4EALDH1A1HSD17B10 | |
| SCHEMBL1119449 | 0.84 | TSHR (0.47) | TSHRKDM4EALDH1A1HSD17B10USP2 | |
| SCHEMBL12112546 | 0.84 | MAPT (0.47) | TSHRKDM4EALDH1A1HSD17B10USP2 | |
| SCHEMBL12112555 | 0.84 | MRGPRX4 (0.49) | KITTSHRKDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8329739-B2 | Phenylimidazole compounds | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2012-12-11 | — | — | US | disclosed |
| US-20110275823-A1 | PHENYLIMIDAZOLE COMPOUNDS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2011-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275823-A1 | PHENYLIMIDAZOLE COMPOUNDS | GPR119, PNLIP, LPL | KIT 1532/4885TSHR 294/4885KDM4E 1190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.