SCHEMBL12113079

SCHEMBL12113079

CNC(=O)c1cc(C#N)cc(C)c1NC(=O)c1cc(Cn2nc3ccc(F)cc3n2)nn1-c1ncccc1Cl

nearest known ligand 0.54

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 15/20 0.36
SLC2A3 P11169 15/20 0.36
SLC2A4 P14672 15/20 0.36
SLC2A2 P11168 5/20 0.36
ADORA3 P0DMS8 1/20 0.34
HRH2 P25021 1/20 0.34
HRH1 P35367 1/20 0.34
PTGER4 P35408 1/20 0.34
PPARG P37231 1/20 0.33
CHRNA7 P36544 1/20 0.33
GPR6 P46095 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12113086 0.93 KMT2A (0.34) SLC2A1SLC2A3SLC2A4SLC2A2PPARG
SCHEMBL12113110 0.92 SLC2A1 (0.36) SLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL12113072 0.91 CHRNA7 (0.34) CHRNA7
SCHEMBL12113124 0.91 SLC2A1 (0.36) SLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL12113078 0.89 SLC2A1 (0.35) SLC2A1SLC2A3SLC2A4SLC2A2ADORA3
SCHEMBL12117045 0.88 SLC2A1 (0.41) SLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL12112989 0.88 PPARG (0.37) SLC2A1SLC2A3SLC2A4SLC2A2PPARG
SCHEMBL12113127 0.88 DHODH (0.34) SLC2A1SLC2A3SLC2A4SLC2A2PPARG
SCHEMBL12112961 0.85 PPARG (0.36) SLC2A1SLC2A3SLC2A4PPARGCHRNA7
SCHEMBL12113190 0.85 CACNA1H (0.37) SLC2A1SLC2A3SLC2A4SLC2A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8536202-B2 Triazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2013-09-17 US disclosed
US-8536202-B2 Triazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2013-09-17 US disclosed
US-20110275676-A1 Triazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2011-11-10 US disclosed
US-20110275676-A1 Triazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2011-11-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110275676-A1 Triazole-substituted anthranilamides as pesticides AADAC, NAAA, ANTXR2 SLC2A1 4803/4885SLC2A3 4685/4885SLC2A4 4817/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.