SCHEMBL12113086

SCHEMBL12113086

CNC(=O)c1cc(C#N)cc(C)c1NC(=O)c1cc(Cn2nc3cc(Cl)c(Cl)cc3n2)nn1-c1ncccc1Cl

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.34
SLC2A1 P11166 7/20 0.33
SLC2A3 P11169 7/20 0.33
SLC2A4 P14672 7/20 0.33
DHODH Q02127 2/20 0.33
SLC2A2 P11168 1/20 0.33
PDE4A P27815 1/20 0.33
PDE4B Q07343 1/20 0.33
PDE4C Q08493 1/20 0.33
PDE4D Q08499 1/20 0.33
PKM P14618 1/20 0.32
GCK P35557 3/20 0.32
KCNH2 Q12809 3/20 0.32
PPARG P37231 1/20 0.31
XIAP P98170 1/20 0.31
BIRC2 Q13490 1/20 0.31
PDE5A O76074 1/20 0.31
MALT1 Q9UDY8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12113079 0.93 SLC2A1 (0.36) SLC2A1SLC2A3SLC2A4SLC2A2PPARG
SCHEMBL12113110 0.93 SLC2A1 (0.36) KMT2ASLC2A1SLC2A3SLC2A4DHODH
SCHEMBL12113127 0.92 DHODH (0.34) KMT2ASLC2A1SLC2A3SLC2A4DHODH
SCHEMBL12113124 0.91 SLC2A1 (0.36) SLC2A1SLC2A3SLC2A4DHODHSLC2A2
SCHEMBL12113059 0.91 DHODH (0.35) DHODHMALT1
SCHEMBL12117045 0.90 SLC2A1 (0.41) SLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL12113074 0.89 SLC2A1 (0.32) KMT2ASLC2A1SLC2A3SLC2A4DHODH
SCHEMBL11928145 0.88 SLC2A1 (0.32) KMT2ASLC2A1SLC2A3SLC2A4DHODH
SCHEMBL12112977 0.88 KCNH2 (0.36) SLC2A1SLC2A3SLC2A4DHODHSLC2A2
SCHEMBL12112979 0.88 CACNA1H (0.34) SLC2A1SLC2A3SLC2A4DHODHSLC2A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8536202-B2 Triazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2013-09-17 US disclosed
US-8536202-B2 Triazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2013-09-17 US disclosed
US-20110275676-A1 Triazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2011-11-10 US disclosed
US-20110275676-A1 Triazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2011-11-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110275676-A1 Triazole-substituted anthranilamides as pesticides AADAC, NAAA, ANTXR2 KMT2A 936/4885SLC2A1 4803/4885SLC2A3 4685/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.