Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | GPR3 | P46089 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12116368 | 0.92 | L3MBTL1 (0.41) | RXRARXRBKDM4EALDH1A1MAOB | |
| SCHEMBL12116365 | 0.92 | L3MBTL1 (0.41) | RXRARXRBKDM4EALDH1A1MAOB | |
| SCHEMBL12116351 | 0.90 | GPR3 (0.42) | RXRARXRBKDM4EHPGDHSD17B10 | |
| SCHEMBL13309435 | 0.90 | KDM4E (0.40) | RXRARXRBKDM4EHSD17B10MAOB | |
| SCHEMBL2609897 | 0.89 | L3MBTL1 (0.42) | RXRARXRBKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL12647527 | 0.88 | L3MBTL1 (0.41) | RXRARXRBKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL12116341 | 0.88 | RXRA (0.39) | RXRARXRBKDM4EHPGDHSD17B10 | |
| SCHEMBL24569000 | 0.87 | RXRA (0.38) | RXRARXRBKDM4EHSD17B10MAOB | |
| SCHEMBL2609898 | 0.87 | L3MBTL1 (0.44) | RXRARXRBKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL2609877 | 0.86 | PDK2 (0.35) | RXRARXRBKDM4EMAOBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110272685-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2011-11-10 | — | — | US | disclosed |
| US-20110272685-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2011-11-10 | — | — | US | disclosed |
| WO-2010083873-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2010-07-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110272685-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | SLCO4C1, SLCO2A1, SLCO2B1 | RXRA 4517/4885RXRB 4494/4885KDM4E 3857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.