Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.59 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9996877 | 1.00 | CYP19A1 (0.59) | CYP19A1EPHX1ALDH1A1TSHRMAPT | |
| SCHEMBL6285383 | 0.97 | CYP19A1 (0.59) | CYP19A1EPHX1ALDH1A1TSHRMAPT | |
| SCHEMBL30252989 | 0.94 | CYP19A1 (0.54) | CYP19A1EPHX1ALDH1A1TSHRMAPT | |
| SCHEMBL22097621 | 0.94 | CYP19A1 (0.54) | CYP19A1EPHX1ALDH1A1TSHRMAPT | |
| SCHEMBL21868824 | 0.94 | CYP19A1 (0.54) | CYP19A1EPHX1ALDH1A1TSHRMAPT | |
| SCHEMBL12449349 | 0.94 | CYP19A1 (0.54) | CYP19A1EPHX1ALDH1A1TSHRMAPT | |
| SCHEMBL12449333 | 0.94 | CYP19A1 (0.54) | CYP19A1EPHX1ALDH1A1TSHRMAPT | |
| SCHEMBL121175 | 0.94 | CYP19A1 (0.54) | CYP19A1EPHX1ALDH1A1TSHRMAPT | |
| SCHEMBL19911164 | 0.94 | CYP19A1 (0.56) | CYP19A1EPHX1ALDH1A1TSHRMAPT | |
| SCHEMBL8576017 | 0.94 | CYP19A1 (0.56) | CYP19A1EPHX1ALDH1A1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1245 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4691492-A2 | LIQUID COMPOSITIONS | Kenvue Brands LLC (US) | 2026-02-11 | — | — | EP | claimed |
| EP-3908266-B1 | LIQUID COMPOSITIONS | KENVUE BRANDS LLC (US) | 2025-10-15 | — | — | EP | claimed |
| EP-3817575-B1 | SOLUBILISATION OF COOLING AGENTS OF LOW SOLUBILITY | SYMRISE AG (DE) | 2025-10-15 | — | — | EP | claimed |
| US-20250163006-A1 | New Coolants, and Preparations Containing Same | SYMRISE AG (DE) | 2025-05-22 | — | — | US | claimed |
| US-20250154123-A1 | COOLING COMPOUNDS AND COMPOSITIONS | V MANE FILS (FR) | 2025-05-15 | — | — | US | claimed |
| US-20250066320-A1 | Active Ingredients with Sialagogue and Tingling/Fizzy Effect, and Preparations Containing Same | SYMRISE AG (DE) | 2025-02-27 | — | — | US | claimed |
| WO-2025026525-A1 | HETEROCYCLIC COMPOUNDS AS PHYSIOLOGICAL COOLANTS | SYMRISE AG (DE) | 2025-02-06 | — | — | WO | claimed |
| EP-4469439-A1 | NEW COOLANTS, AND PREPARATIONS CONTAINING SAME | Symrise AG (DE) | 2024-12-04 | — | — | EP | claimed |
| CN-118984825-A | Novel cooling agent and preparation containing same | 西姆莱斯股份公司 | 2024-11-19 | — | — | CN | claimed |
| EP-4460283-A1 | COOLING COMPOUNDS AND COMPOSITIONS | V. Mane Fils (FR) | 2024-11-13 | — | — | EP | claimed |
| EP-1446019-A1 | WATER CONTINUOUS FOOD PRODUCT WITH COOLING FLAVOUR | UNILEVER N.V. (NL) | 2004-08-18 | — | — | EP | claimed |
| US-20040141927-A1 | Chewing gums, confections, mouthwashes, mouth sprays and edible thin film products | WM. WRIGLEY JR. COMPANY | 2004-07-22 | — | — | US | claimed |
| WO-2004045590-A1 | ORAL PRODUCTS CONTAINING NOVEL FLAVOR COMPOSITION | WM. WRIGLEY JR. COMPANY (US) | 2004-06-03 | — | — | WO | claimed |
| WO-2004019922-A1 | BREATH FRESHENING AND ORAL CLEANSING PRODUCT USING CITRAL | WM. WRIGLEY JR. COMPANY (US) | 2004-03-11 | — | — | WO | claimed |
| WO-2004019870-A2 | BREATH FRESHENING AND ORAL CLEANSING PRODUCT USING SALICYLALDEHYDE | WM. WRIGLEY JR. COMPANY (US) | 2004-03-11 | — | — | WO | claimed |
| WO-2004019800-A2 | BREATH FRESHENING AND ORAL CLEANSING PRODUCT | WM. WRIGLEY JR. COMPANY (US) | 2004-03-11 | — | — | WO | claimed |
| WO-2004019867-A2 | BREATH FRESHENING AND ORAL CLEANSING PRODUCT USING CARDAMOM OIL | WM. WRIGLEY JR. COMPANY (US) | 2004-03-11 | — | — | WO | claimed |
| WO-2004019802-A2 | BREATH FRESHENING AND ORAL CLEANSING PRODUCT USING CARVACROL | WM. WRIGLEY JR. COMPANY (US) | 2004-03-11 | — | — | WO | claimed |
| WO-2004019871-A2 | BREATH FRESHENING AND ORAL CLEANSING PRODUCT USING GERANIOL | WM. WRIGLEY JR. COMPANY (US) | 2004-03-11 | — | — | WO | claimed |
| WO-2003043431-A1 | WATER CONTINUOUS FOOD PRODUCT WITH COOLING FLAVOUR | UNILEVER N.V. (NL) | 2003-05-30 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250066320-A1 | Active Ingredients with Sialagogue and Tingling/Fizzy Effect, and Preparations Containing Same | TAS2R5, TAS2R7, TAS2R8 | CYP19A1 4090/4885EPHX1 2617/4885ALDH1A1 2893/4885 |
| US-20250163006-A1 | New Coolants, and Preparations Containing Same | TTR, TAS2R5, TAS2R50 | CYP19A1 2595/4885EPHX1 2081/4885ALDH1A1 811/4885 |
| US-20250154123-A1 | COOLING COMPOUNDS AND COMPOSITIONS | CBR3, DECR1, DECR2 | CYP19A1 148/4885EPHX1 479/4885ALDH1A1 1426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.