Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 20/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1319744 | 0.92 | MMP13 (0.83) | MMP13 | |
| SCHEMBL1317151 | 0.92 | MMP13 (1.00) | MMP13 | |
| SCHEMBL1319745 | 0.92 | MMP13 (0.83) | MMP13 | |
| SCHEMBL7909579 | 0.91 | MMP13 (1.00) | MMP13 | |
| SCHEMBL7914349 | 0.91 | MMP13 (1.00) | MMP13 | |
| SCHEMBL12123483 | 0.88 | MMP13 (0.84) | MMP13 | |
| SCHEMBL1318439 | 0.86 | MMP13 (1.00) | MMP13 | |
| SCHEMBL1317771 | 0.86 | MMP13 (1.00) | MMP13 | |
| SCHEMBL7920066 | 0.85 | MMP13 (0.82) | MMP13 | |
| SCHEMBL1316149 | 0.85 | MMP13 (0.82) | MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110275625-A1 | Heteroaryl Diamide Compounds Useful as MMP-13 Inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275625-A1 | Heteroaryl Diamide Compounds Useful as MMP-13 Inhibitors | MMP13, MMP3, MMP11 | MMP13 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.