MMP11 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL3862254	0.70	3/20
SCHEMBL3862257	0.70	3/20
SCHEMBL6274298	0.70	3/20
SCHEMBL8276969	0.70	3/20
SCHEMBL3888661	0.65	3/20
SCHEMBL3888663	0.65	3/20
SCHEMBL3888666	0.65	3/20
SCHEMBL5399966	0.67	2/20
SCHEMBL5556658	0.67	2/20
SCHEMBL1711383	0.66	2/20
SCHEMBL5381814	0.66	2/20
SCHEMBL29472048	0.66	2/20
SCHEMBL3867957	0.65	2/20
SCHEMBL5379426	0.64	2/20
SCHEMBL31516067	0.63	2/20
SCHEMBL5384805	0.61	2/20
SCHEMBL6274299	0.59	2/20
SCHEMBL5383412	0.58	2/20
SCHEMBL7398288	0.58	2/20
SCHEMBL7391501	0.57	2/20

Clinical trials — most relevant to MMP11 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Estimation of MMP-8 Levels in GCF and Serum and Its Correlation With Wound Healing and Clinical Outcomes After Coronally Advanced Flap and Subepithelial Connective Tissue Graft for Root Coverage in Recession Defects: A CLINICO-BIOCHEMICAL STUDY	PHASE4	SUSPENDED
Host Modulatory Effects of β-glucan on Localized Aggressive Periodontitis	PHASE4	COMPLETED
Doxycycline In Lymphangioleiomyomatosis (LAM)	PHASE4	COMPLETED
Sputum Matrix Metalloproteinases (MMP) mRNA and Montelukast	PHASE2	COMPLETED
A Study of Sorafenib in Patients With Chemonaive Metastatic Uveal Melanoma	PHASE2	UNKNOWN
A Phase I Study of Oral COL-3 (NSC-683551), a Matrix Metalloproteinase Inhibitor, in Patients With Refractory Metastatic Cancer	PHASE1	COMPLETED
The Role of Matrix Metalloproteinases (MMPs) in Orthodontic Tooth Movement	PHASE1	COMPLETED
Re-evaluation of Some Old Rheumatoid Arthritis Therapy: A Randomized Controlled Trial	nan	COMPLETED
Periodontal Health in Post COVID-19 Patients	nan	UNKNOWN
Case-control Study on Matrix Metalloproteinase Levels in Tissue in Patients With Keloid Scar	nan	COMPLETED
The Impact of Pregnancy and Pregnancy-associated Hypertension on Human Uterine Myometrial Artery Reactivity	nan	WITHDRAWN
Influence of Statins in Artery Aneurysms	nan	UNKNOWN
Evaluation of Dentinal Fluid for the Presence of Matrix Metalloproteinase 9 (MMP-9) in Pulpal Inflammation	nan	COMPLETED
The Effect of Exercise Training on lncRNA Expression in Rheumatoid Arthritis	nan	RECRUITING
Role of A Disintegrin and Metalloproteinase (ADAM) in Epithelial Dysfunction	nan	COMPLETED
Apoptotic Changes in Gingiva Caused by Smoking	nan	COMPLETED
Detection of Cancer-Specific Active Proteases in Blood Via Fluorescence	nan	WITHDRAWN
Matrix Metalloproteinases After Surgery and/or Radiofrequency Ablation in Patients With Liver Metastases From Colorectal Cancer	nan	COMPLETED
Evaluation of Different Serum Cartilage Biomarkers in the Acute Response to Walking and Cycling in Healthy Male Subjects	nan	AVAILABLE
miRNA-452 in Patients With Preeclampsia and Its Correlation With MMP-9	nan	COMPLETED
Plasma and Scarring of Diabetic Ulcers	nan	COMPLETED
The Effect of Non-surgical Periodontal Therapy Plus Doxycycline on HbA1c in Patients With Type 2 Diabetes Mellitus	nan	COMPLETED
Pathology, Venous Disease, and Clinical Correlations	nan	UNKNOWN
The Effects of Sodium Fluoride and Chlorhexidine Use on Salivary IL-6 and Matrix Metalloproteinase Levels in Children With Active Caries	nan	RECRUITING
Role of Extracellular Matrix in the Development of Airway Remodeling in Asthma	nan	UNKNOWN
Peri-implantitis and MMP-8	nan	COMPLETED
Matrix Metalloproteinase (MMP) in Heart Failure	nan	COMPLETED
Characterization of Pulp Inflammation: an Observational Study Using Biological Samples Collected During Routine Dental Care	nan	NOT_YET_RECRUITING
Influence of Short AV Delay Permanent Pacing on Matrix Metalloproteinase Levels	nan	COMPLETED
Matrix Metalloproteinases and Human Papillomavirus in Dysplasias and Cancers of the Cervix	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a MMP11 binder may also engage these)

Protein	Name	Similarity
Q499S5	—	0.999	Q499S5 →
Q9R0S3	—	0.994	Q9R0S3 →
Q3U435	—	0.993	Q3U435 →
Q02853	—	0.992	Q02853 →
MMP17	Matrix metalloproteinase-17	0.991	landscape →
Q9H239	—	0.990	Q9H239 →
MMP24	Matrix metalloproteinase-24	0.988	landscape →
MMP25	Matrix metalloproteinase-25	0.988	landscape →
Q95220	—	0.987	Q95220 →
P52176	—	0.986	P52176 →
P53690	—	0.986	P53690 →
MMP14	Matrix metalloproteinase-14	0.984	landscape →
MMP15	Matrix metalloproteinase-15	0.983	landscape →
Q99542	—	0.983	Q99542 →
MMP9	Matrix metalloproteinase-9	0.983	landscape →
Q5RES1	—	0.983	Q5RES1 →
Q10739	—	0.982	Q10739 →
O54732	—	0.982	O54732 →
Q9JHI0	—	0.982	Q9JHI0 →
O55123	—	0.982	O55123 →
P41245	—	0.982	P41245 →
P41246	—	0.981	P41246 →
Q9H324	—	0.981	Q9H324 →
INSRR	Insulin receptor-related protein	0.981	landscape →
Q9R0S2	—	0.981	Q9R0S2 →
Q96SM3	—	0.981	Q96SM3 →
Q9GLE4	—	0.981	Q9GLE4 →
Q8BYG9	—	0.980	Q8BYG9 →
Q99PW6	—	0.980	Q99PW6 →
P58459	—	0.980	P58459 →