Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP3 | P08254 | 1/20 | 0.50 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 2/20 | 0.39 |
| ▸ | GLP1R | P43220 | 6/20 | 0.38 |
| ▸ | AHR | P35869 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7237225 | 0.83 | GLP1R (0.48) | MMP1MMP2MMP3MAPK13CDK1 | |
| SCHEMBL12124147 | 0.81 | MAPK13 (0.53) | MMP1MMP2MMP3MAPK13CDK1 | |
| SCHEMBL1291867 | 0.78 | PGK1 (0.57) | MMP1MMP2MMP3 | |
| SCHEMBL6305874 | 0.78 | GLP1R (0.53) | MMP1MMP2MMP3MAPK13CDK1 | |
| SCHEMBL1291759 | 0.78 | PGK1 (0.57) | NQO2GAA | |
| SCHEMBL29512047 | 0.75 | NQO2 (0.52) | MMP1MMP2MMP3MAPK13CDK1 | |
| SCHEMBL29558616 | 0.75 | TDP1 (0.50) | MMP1MMP2MMP3MAPK13CDK1 | |
| SCHEMBL2245783 | 0.75 | NQO2 (0.52) | MMP1MMP2MMP3MAPK13CDK1 | |
| SCHEMBL405486 | 0.75 | TDP1 (0.50) | MMP1MMP2MMP3MAPK13CDK1 | |
| SCHEMBL8647953 | 0.71 | MMP1 (0.33) | MMP1MMP2MMP3MAPK13CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130224624-A1 | PROTON EXCHANGE MEMBRANES | RENO (US) | 2013-08-29 | — | — | US | disclosed |
| US-20110033776-A1 | PROTON EXCHANGE MEMBRANES | Board of regents of the Nevada System of Higher Education, on Behalf of the University of | 2011-02-10 | — | — | US | disclosed |
| US-6548499-B1 | N-(1-Azabicyclo(2.2.2)octanyl-3-pyridinyl)-3-(2-pyridinyl)-2 -quinoxalinamine, for example; treating various chemokine mediated diseases | MILLENNIUM PHARMACEUTICALS, INC. | 2003-04-15 | — | — | US | disclosed |
| WO-1999042463-A1 | SUBSTITUTED QUINOXALINE DERIVATIVES AS INTERLEUKIN-8 RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1999-08-26 | — | — | WO | disclosed |