SCHEMBL405486

SCHEMBL405486

Clc1cc2nc(Cl)c(Cl)nc2cc1Cl

nearest known ligand 0.60

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.50
MMP1 P03956 1/20 0.48
MMP2 P08253 1/20 0.48
MMP3 P08254 1/20 0.48
MAPK13 O15264 1/20 0.48
CDK1 P06493 1/20 0.48
PIM1 P11309 1/20 0.48
DYRK1A Q13627 1/20 0.48
PIM3 Q86V86 1/20 0.48
CLK4 Q9HAZ1 1/20 0.48
NQO2 P16083 2/20 0.41
GLP1R P43220 6/20 0.40
PGK1 P00558 2/20 0.37
GAA P10253 1/20 0.37
HTT P42858 1/20 0.37
HRH4 Q9H3N8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29558616 1.00 TDP1 (0.50) TDP1MMP1MMP2MMP3MAPK13
SCHEMBL11540011 0.86 TDP1 (0.56) TDP1MMP1MMP2MMP3MAPK13
SCHEMBL12124147 0.86 MAPK13 (0.53) MMP1MMP2MMP3MAPK13CDK1
SCHEMBL4921900 0.81 GLP1R (0.52) TDP1MMP1MMP2MMP3MAPK13
SCHEMBL6307514 0.81 HRH4 (0.47) TDP1MMP1MMP2MMP3MAPK13
SCHEMBL405345 0.81 ALDH1A1 (0.45) TDP1MMP1MMP2MMP3NQO2
SCHEMBL1291790 0.81 TDP1 (0.40) TDP1MMP1MMP2MMP3MAPK13
SCHEMBL404267 0.81 MAPT (0.45) TDP1MMP1MMP2MMP3MAPK13
SCHEMBL29512047 0.80 NQO2 (0.52) MMP1MMP2MMP3MAPK13CDK1
SCHEMBL2245783 0.80 NQO2 (0.52) MMP1MMP2MMP3MAPK13CDK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1575070-B Organic light emitting device employing doped hole transport layer and/or hole injection layer SAMSUNG MOBILE DISPLAY CO LTD 2012-05-02 CN claimed
US-7875877-B2 Organic thin film transistor and flat panel display device having the same SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2011-01-25 US claimed
US-7771843-B2 Organic light-emitting device employing doped hole transporting layer and/or hole injecting layer SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2010-08-10 US claimed
US-7671359-B2 Thin film transistor, a method for preparing the same and a flat panel display employing the same SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2010-03-02 US claimed
US-20070090351-A1 Organic thin film transistor and flat panel display device having the same SAMSUNG SDI CO., LTD. (KR) 2007-04-26 US claimed
CN-1841807-A A thin film transistor, a method for preparing the same and a flat panel display therewith SAMSUNG SDI CO LTD (KR) 2006-10-04 CN claimed
US-20060169974-A1 Thin film transistor, a method of manufacturing the same, and a flat panel display device including the thin film transistor SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2006-08-03 US claimed
US-20060160280-A1 Thin film transistor, a method for preparing the same and a flat panel display employing the same SAMSUNG DISPLAY CO., LTD. (KR) 2006-07-20 US claimed
EP-1681733-A1 Organic thin film transistor Samsung SDI Co., Ltd. (KR) 2006-07-19 EP claimed
CN-1575070-A Organic light-emitting device employing doped hole transporting layer and/or hole injecting layer SAMSUNG SDI CO LTD (KR) 2005-02-02 CN claimed
US-20040265630-A1 Organic light-emitting device employing doped hole transporting layer and/or hole injecting layer SAMSUNG SDI CO., LTD. (KR) 2004-12-30 US claimed
US-5939568-A Accelerated catalysis of olefinic epoxidations THE SCRIPPS RESEARCH INSTITUTE (US) 1999-08-17 US claimed
WO-1998033786-A9 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS 1998-12-30 WO claimed
WO-1998033786-A1 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS THE SCRIPPS RESEARCH INSTITUTE (US) 1998-08-06 WO claimed
US-4119460-A FUSED CARBOCYCLIC RING COMPOUNDS, POLYPHENYL COMPOUNDS NITROGEN-FREE POLYARYLATED COMPOUNDS EASTMAN KODAK COMPANY (US) 1978-10-10 US claimed
CN-114380753-B Aryl or heteroaryl substituted quinoxaline-2, 3-diamine compound and antibacterial application thereof 中国医学科学院药物研究所 2024-02-27 CN disclosed
US-11618744-B2 Benzoimidazoles as prolyl hydroxylase inhibitors JANSSEN PHARMACEUTICA NV (BE) 2023-04-04 US disclosed
US-4160666-A Polymeric chemical sensitizers for organic photoconductive compositions EASTMAN KODAK COMPANY (US) 1979-07-10 US disclosed
US-4119460-A FUSED CARBOCYCLIC RING COMPOUNDS, POLYPHENYL COMPOUNDS NITROGEN-FREE POLYARYLATED COMPOUNDS EASTMAN KODAK COMPANY (US) 1978-10-10 US disclosed
US-3988455-A Ditetrazolo(1,5-a:5',1'-c)quinoxalines for control of soil-borne phytopathogens ELI LILLY AND COMPANY (US) 1976-10-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11618744-B2 Benzoimidazoles as prolyl hydroxylase inhibitors P4HA1, PAH, EGLN3 TDP1 1767/4885MMP1 1029/4885MMP2 472/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.