SCHEMBL987143

SCHEMBL987143

Cc1ccc([Si](c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.53
ACHE P22303 2/20 0.53
TSHR P16473 1/20 0.53
ALOX12 P18054 1/20 0.53
TDP1 Q9NUW8 3/20 0.44
HPGD P15428 3/20 0.44
NPC1 O15118 4/20 0.41
RAB9A P51151 4/20 0.41
NFKB1 P19838 2/20 0.41
NFKB2 Q00653 2/20 0.41
RELA Q04206 2/20 0.41
POLB P06746 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
ALDH1A1 P00352 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7265559 1.00 LMNA (0.53) LMNAACHETSHRALOX12TDP1
SCHEMBL12124367 1.00 LMNA (0.53) LMNAACHETSHRALOX12TDP1
SCHEMBL2454173 1.00 LMNA (0.53) LMNAACHETSHRALOX12TDP1
SCHEMBL12124345 1.00 LMNA (0.53) LMNAACHETSHRALOX12TDP1
SCHEMBL12124338 0.93 RAB9A (0.47) LMNAACHETSHRALOX12TDP1
SCHEMBL14208875 0.93 RAB9A (0.47) LMNAACHETSHRALOX12TDP1
SCHEMBL22156067 0.93 RAB9A (0.47) LMNAACHETSHRALOX12TDP1
SCHEMBL12367285 0.93 RAB9A (0.47) LMNAACHETSHRALOX12TDP1
SCHEMBL23661031 0.89 ACHE (0.56) LMNAACHETSHRALOX12TDP1
SCHEMBL20427762 0.89 CES2 (0.42) LMNAACHETSHRALOX12TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12565587-B2 Nonlinear optical chromophores having short-chain bridge structures, low optical loss materials containing the same, and methods for preparing the same LIGHTWAVE LOGIC, INC. (US) 2026-03-03 US disclosed
US-20250066667-A1 Nonlinear Optical Chromophores Having Tetrahydrocarbazole Donor Groups, Lyotropic Compositions Containing the Same, and Methods of Poling Such Compositions LIGHTWAVE LOGIC, INC. (US) 2025-02-27 US disclosed
US-12173217-B2 Nonlinear optical chromophores having tetrahydrocarbazole donor groups, lyotropic compositions containing the same, and methods of poling such compositions LIGHTWAVE LOGIC, INC. (US) 2024-12-24 US disclosed
EP-4460726-A1 NONLINEAR OPTICAL CHROMOPHORES HAVING SHORT-CHAIN BRIDGE STRUCTURES, LOW OPTICAL LOSS MATERIALS CONTAINING THE SAME, AND METHODS FOR PREPARING THE SAME Lightwave Logic, Inc. (US) 2024-11-13 EP disclosed
EP-4445212-A1 NONLINEAR OPTICAL CHROMOPHORES HAVING TETRAHYDROCARBAZOLE DONOR GROUPS, LYOTROPIC COMPOSITIONS CONTAINING THE SAME, AND METHODS OF POLING SUCH COMPOSITIONS Lightwave Logic, Inc. (US) 2024-10-16 EP disclosed
US-20240247192-A1 Nonlinear Optical Chromophores Having Tetrahydrocarbazole Donor Groups, Lyotropic Compositions Containing the Same, and Methods of Poling Such Compositions LIGHTWAVE LOGIC, INC. (US) 2024-07-25 US disclosed
WO-2024126322-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2024-06-20 WO disclosed
US-11976232-B2 Nonlinear optical chromophores having tetrahydrocarbazole donor groups, lyotropic compositions containing the same, and methods of poling such compositions LIGHTWAVE LOGIC, INC. (US) 2024-05-07 US disclosed
US-20240025927-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-01-25 US disclosed
US-20240025927-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-01-25 US disclosed
US-20090191426-A2 ORGANIC COMPOUND, CHARGE-TRANSPORTING MATERIAL, AND ORGANIC ELECTROLUMINESCENT ELEMENT PIONEER CORPORATION (JP) 2009-07-30 US disclosed
US-20090165860-A1 Electroluminescent device using electroluminescent compounds GRACEL DISPLAY INC. (KR) 2009-07-02 US disclosed
US-20090078317-A1 Organometalic compounds for electroluminescence and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-03-26 US disclosed
US-20080145699-A1 Organic Compound, Charge-Transporting Material, and Organic Electroluminescent Element PIONEER CORPORATION (JP) 2008-06-19 US disclosed
US-20070231598-A1 Electroluminescent Polymers MERCK PATENT GMBH PATENT & SCIENTIFIC INFORMATION (DE) 2007-10-04 US disclosed
US-20070176147-A1 Novel material mixtures for use in electroluminescence MERCK PATENT GMBH (DE) 2007-08-02 US disclosed
EP-0405560-B2 Preparation of tertiary-hydrocarbylsilyl compounds DOW CORNING TORAY SILICONE (JP) 1998-08-12 EP disclosed
EP-0245228-B1 CATALYTIC PROCESS FOR PRODUCING SILAHYDROCARBONS MONSANTO COMPANY (US) 1990-12-12 EP disclosed
EP-0245228-A1 Catalytic process for producing silahydrocarbons MONSANTO COMPANY (US) 1987-11-11 EP disclosed
US-4650891-A HALOSILANE AND GRIGNARD REAGENT, CYANIDE CATALYST MONSANTO COMPANY (US) 1987-03-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12565587-B2 Nonlinear optical chromophores having short-chain bridge structures, low optical loss materials containing the same, and methods for preparing the same CRY2, GJB2, CYBA LMNA 79/4885ACHE 2475/4885TSHR 3960/4885
US-20090078317-A1 Organometalic compounds for electroluminescence and organic electroluminescent device using the same OCIAD1, L1CAM, OCIAD2 LMNA 1976/4885ACHE 745/4885TSHR 4611/4885
US-20070231598-A1 Electroluminescent Polymers MAP1LC3C, LAS1L, PARG LMNA 4323/4885ACHE 3107/4885TSHR 4168/4885
US-20090191426-A2 ORGANIC COMPOUND, CHARGE-TRANSPORTING MATERIAL, AND ORGANIC ELECTROLUMINESCENT ELEMENT SLC39A3, SLCO2A1, SLC39A11 LMNA 2784/4885ACHE 3305/4885TSHR 3892/4885
US-20240025927-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, ODC1 LMNA 2681/4885ACHE 592/4885TSHR 3948/4885
US-20080145699-A1 Organic Compound, Charge-Transporting Material, and Organic Electroluminescent Element SLC39A3, SLCO2A1, SLC39A11 LMNA 2784/4885ACHE 3305/4885TSHR 3892/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.