Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12124683 | 0.99 | — | — | |
| SCHEMBL12124681 | 0.94 | — | — | |
| SCHEMBL12124580 | 0.88 | — | — | |
| SCHEMBL12124554 | 0.86 | HTR7 (0.69) | — | |
| SCHEMBL6846689 | 0.86 | — | — | |
| SCHEMBL12124690 | 0.85 | SLC6A2 (0.66) | — | |
| SCHEMBL12124682 | 0.84 | HTR7 (0.73) | — | |
| SCHEMBL13875126 | 0.83 | KDM4E (0.69) | KDM4EGAA | |
| SCHEMBL12124688 | 0.83 | SLC6A2 (0.67) | — | |
| SCHEMBL8119654 | 0.82 | KCNH2 (0.67) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3102204-B1 | HIGHLY SELECTIVE SIGMA 1 RECEPTOR LIGANDS AND RADIOLIGANDS AS PROBES IN NOCICEPTIVE PROCESSING AND THE PATHOPHYSIOLOGICAL STUDY OF MEMORY DEFICITS AND COGNITIVE DISORDERS | THE UNIV OF MISSISSIPPI (US) | 2021-05-05 | — | — | EP | disclosed |
| US-9724435-B2 | Highly selective sigma receptor ligands and radioligands as probes in nociceptive processing and the pathphysiological study of memory deficits and cognitive disorders | THE UNIVERSITY OF MISSISSIPPI (US) | 2017-08-08 | — | — | US | disclosed |
| US-9724435-B2 | Highly selective sigma receptor ligands and radioligands as probes in nociceptive processing and the pathphysiological study of memory deficits and cognitive disorders | THE UNIVERSITY OF MISSISSIPPI (US) | 2017-08-08 | — | — | US | disclosed |
| US-9604926-B2 | Highly selective sigma receptor radioligands | THE UNIVERSITY OF MISSISSIPPI (US) | 2017-03-28 | — | — | US | disclosed |
| US-9604926-B2 | Highly selective sigma receptor radioligands | THE UNIVERSITY OF MISSISSIPPI (US) | 2017-03-28 | — | — | US | disclosed |
| US-20140328755-A1 | HIGHLY SELECTIVE SIGMA RECEPTOR LIGANDS AND RADIOLIGANDS AS PROBES IN NOCICEPTIVE PROCESSING AND THE PATHPHYSIOLOGICAL STUDY OF MEMORY DEFICITS AND COGNITIVE DISORDERS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2014-11-06 | — | — | US | disclosed |
| US-20140328755-A1 | HIGHLY SELECTIVE SIGMA RECEPTOR LIGANDS AND RADIOLIGANDS AS PROBES IN NOCICEPTIVE PROCESSING AND THE PATHPHYSIOLOGICAL STUDY OF MEMORY DEFICITS AND COGNITIVE DISORDERS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2014-11-06 | — | — | US | disclosed |
| US-20110280804-A1 | HIGHLY SELECTIVE SIGMA RECEPTOR RADIOLIGANDS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2011-11-17 | — | — | US | disclosed |
| US-20110280804-A1 | HIGHLY SELECTIVE SIGMA RECEPTOR RADIOLIGANDS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2011-11-17 | — | — | US | disclosed |
| US-20100329978-A1 | HIGHLY SELECTIVE SIGMA RECEPTOR LIGANDS | UNIVERSITY OF MISSISSIPPI (US) | 2010-12-30 | — | — | US | disclosed |
| US-20100329978-A1 | HIGHLY SELECTIVE SIGMA RECEPTOR LIGANDS | UNIVERSITY OF MISSISSIPPI (US) | 2010-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100329978-A1 | HIGHLY SELECTIVE SIGMA RECEPTOR LIGANDS | SIGMAR1, OPRL1, CNR1 | KDM4E 4244/4885GAA 4551/4885 |
| US-20140328755-A1 | HIGHLY SELECTIVE SIGMA RECEPTOR LIGANDS AND RADIOLIGANDS AS PROBES IN NOCICEPTIVE PROCESSING AND THE PATHPHYSIOLOGICAL STUDY OF MEMORY DEFICITS AND COGNITIVE DISORDERS | SIGMAR1, OPRL1, OPRK1 | KDM4E 4745/4885GAA 3116/4885 |
| US-20110280804-A1 | HIGHLY SELECTIVE SIGMA RECEPTOR RADIOLIGANDS | SIGMAR1, MSR1, TMEM97 | KDM4E 3506/4885GAA 4357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.