Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | ALPL | P05186 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | ALPI | P09923 | 1/20 | 0.54 |
| ▸ | ALPG | P10696 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | MMP14 | P50281 | 1/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17550007 | 0.82 | MAPT (0.58) | THRBKMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL23259602 | 0.79 | THRB (0.58) | THRBKMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL28417737 | 0.79 | THRB (0.58) | THRBKMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL1942693 | 0.79 | THRB (0.96) | THRBKMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL52298 | 0.79 | THRB (0.96) | THRBKMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL20138219 | 0.79 | THRB (0.96) | THRBKMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL16746723 | 0.79 | CYP1A2 (0.47) | THRBKMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL10999478 | 0.79 | THRB (0.62) | THRBKMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL10294618 | 0.79 | THRB (0.96) | THRBKMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL506289 | 0.79 | THRB (0.96) | THRBKMT2AMEN1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9803240-B2 | Stabilized nucleic acid dark quencher-fluorophore probes | BIOSEARCH TECHNOLOGIES, INC. (US) | 2017-10-31 | — | — | US | disclosed |
| US-9139610-B2 | Dark quenchers for donor-acceptor energy transfer | BIOSEARCH TECHNOLOGIES, INC. (US) | 2015-09-22 | — | — | US | disclosed |
| US-20150197792-A1 | DARK QUENCHERS FOR DONOR-ACCEPTOR ENERGY TRANSFER | BIOSEARCH TECHNOLOGIES, INC. | 2015-07-16 | — | — | US | disclosed |
| US-20140194611-A1 | STABILIZED NUCLEIC ACID DARK QUENCHER-FLUOROPHORE PROBES | BIOSEARCH TECHNOLOGIES, INC. (US) | 2014-07-10 | — | — | US | disclosed |
| US-20140187763-A1 | DARK QUENCHERS FOR DONOR-ACCEPTOR ENERGY TRANSFER | BIOSEARCH TECHNOLOGIES, INC. | 2014-07-03 | — | — | US | disclosed |
| US-8674094-B2 | Stabilized nucleic acid dark quencher-fluorophore probes | BIOSEARCH TECHNOLOGIES, INC. (US) | 2014-03-18 | — | — | US | disclosed |
| US-8466266-B2 | Stabilized nucleic acid dark quencher-fluorophore probes | BIOSEARCH TECHNOLOGIES, INC. (US) | 2013-06-18 | — | — | US | disclosed |
| US-20110282041-A1 | STABILIZED NUCLEIC ACID DARK QUENCHER-FLUOROPHORE PROBES | BIOSEARCH TECHNOLOGIES, INC. (US) | 2011-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110282041-A1 | STABILIZED NUCLEIC ACID DARK QUENCHER-FLUOROPHORE PROBES | DDX1, DDX18, DDX3X | THRB 3947/4885KMT2A 984/4885MEN1 3912/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.