Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 3/20 | 0.47 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MPL | P40238 | 1/20 | 0.40 |
| ▸ | CTRC | Q99895 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16746725 | 0.85 | THRB (0.50) | CYP1A2CYP2A6TSHRTHRBGLO1 | |
| SCHEMBL16746724 | 0.81 | TSHR (0.47) | CYP1A2TSHRTHRBALDH1A1HSD17B10 | |
| SCHEMBL16749787 | 0.79 | MPL (0.65) | CYP1A2TSHRGLO1HSD17B10MPL | |
| SCHEMBL12133347 | 0.79 | THRB (0.62) | CYP1A2CYP2A6TSHRTHRBGLO1 | |
| SCHEMBL15181274 | 0.79 | THRB (0.50) | CYP1A2CYP2A6TSHRTHRBGLO1 | |
| SCHEMBL7482723 | 0.77 | CYP1A2 (0.58) | CYP1A2CYP2A6TSHRTHRBGLO1 | |
| SCHEMBL4119215 | 0.75 | CYP1A2 (0.56) | CYP1A2CYP2A6TSHRTHRBGLO1 | |
| SCHEMBL14118304 | 0.73 | TSHR (0.54) | CYP1A2CYP2A6TSHRTHRBGLO1 | |
| SCHEMBL15957824 | 0.71 | THRB (0.74) | CYP1A2CYP2A6TSHRTHRBGLO1 | |
| SCHEMBL12954917 | 0.70 | THRB (0.63) | CYP1A2TSHRTHRBGLO1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9346958-B2 | Reactive dyes, their preparation and their use | HUNTSMAN INTERNATIONAL LLC (US) | 2016-05-24 | — | — | US | disclosed |
| US-20150143639-A1 | Reactive Dyes, Their Preparation and Their Use | HUNTSMAN INTERNATIONAL LLC | 2015-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150143639-A1 | Reactive Dyes, Their Preparation and Their Use | H1-2, H1-3, H1-4 | CYP1A2 1506/4885CYP2A6 2068/4885TSHR 373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.