SCHEMBL12133682

SCHEMBL12133682

c1ccc(-c2nc(-c3ccc4c(c3)C3(c5ccccc5-c5ccccc53)c3ccccc3-4)nc(-c3ccc4c(c3)C3(c5ccccc5-c5ccccc53)c3ccccc3-4)n2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 6/20 0.47
▸ KMT2A Q03164 6/20 0.47
▸ MAPT P10636 4/20 0.47
▸ HPGD P15428 4/20 0.47
▸ ALDH1A1 P00352 3/20 0.47
▸ PDK2 Q15119 6/20 0.44
▸ NTSR1 P30989 1/20 0.43
▸ LMNA P02545 4/20 0.41
▸ KDM4E B2RXH2 3/20 0.41
▸ GLA P06280 1/20 0.41
▸ L3MBTL1 Q9Y468 1/20 0.41
▸ ADORA2A P29274 3/20 0.41
▸ ADORA1 P30542 3/20 0.41
▸ ADORA3 P0DMS8 2/20 0.39
▸ ADORA2B P29275 2/20 0.39
▸ ALOX15 P16050 1/20 0.39
▸ TSHR P16473 1/20 0.39
▸ POLB P06746 2/20 0.39
▸ OPRK1 P41145 1/20 0.38
▸ SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12133677 1.00 MEN1 (0.47) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL29865478 1.00 MEN1 (0.47) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL132140 1.00 MEN1 (0.47) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL8784125 1.00 MEN1 (0.47) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL12133749 0.98 PDK2 (0.46) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL12133761 0.98 PDK2 (0.46) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL12133751 0.98 PDK2 (0.46) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL19759319 0.98 MEN1 (0.46) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL22436047 0.98 MEN1 (0.46) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL21394230 0.98 PDK2 (0.46) MEN1KMT2AMAPTHPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3457450-B1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2024-06-12 — — EP disclosed
EP-2984152-B2 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2022-01-05 — — EP disclosed
EP-2627730-B1 FORMULATIONS FOR ORGANIC ELECTROLUMINESCENCE DEVICES MERCK PATENT GMBH (DE) 2020-05-06 — — EP disclosed
US-10636990-B2 Organic electroluminescence device MERCK PATENT GMBH (DE) 2020-04-28 — — US disclosed
EP-2748878-B1 ORGANIC ELECTROLUMINESCENCE DEVICE MERCK PATENT GMBH (DE) 2020-04-01 — — EP disclosed
US-20190355911-A1 ORGANIC MIXTURE, ORGANIC COMPOSITION, ORGANIC ELECTRONIC COMPONENT AND PREPARATION METHOD THEREFOR GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) 2019-11-21 — — US disclosed
EP-2371016-B1 ORGANIC LIGHT EMITTING EVICES COMPRISING TRIAZINE DERIVATIVES MERCK PATENT GMBH (DE) 2019-08-07 — — EP disclosed
EP-3457450-A1 ORGANIC ELECTROLUMINESCENT DEVICE Merck Patent GmbH (DE) 2019-03-20 — — EP disclosed
EP-2984152-B1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2018-04-25 — — EP disclosed
US-9905792-B2 Organic light emitting diode and organic light emitting diode display including the same SAMSUNG DISPLAY CO., LTD. (KR) 2018-02-27 — — US disclosed
US-20110284831-A1 ORGANIC ELECTROLUMINESCENCE DEVICE MERCK PATENT GMBH (DE) 2011-11-24 — — US disclosed
US-20110284831-A1 ORGANIC ELECTROLUMINESCENCE DEVICE MERCK PATENT GMBH (DE) 2011-11-24 — — US disclosed
US-8003227-B2 Organic electroluminescent element MERCK PATENT GMBH (DE) 2011-08-23 — — US disclosed
US-8003227-B2 Organic electroluminescent element MERCK PATENT GMBH (DE) 2011-08-23 — — US disclosed
US-20110095282-A1 ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING TRIAZINE DERIVATIVES MERCK PATENT GMBH (DE) 2011-04-28 — — US disclosed
US-20110095282-A1 ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING TRIAZINE DERIVATIVES MERCK PATENT GMBH (DE) 2011-04-28 — — US disclosed
WO-2010102706-A1 ORGANIC ELECTROLUMINESCENCE DEVICE MERCK PATENT GMBH (DE) 2010-09-16 — — WO disclosed
WO-2010072300-A1 ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING TRIAZINE DERIVATIVES MERCK PATENT GMBH (DE) 2010-07-01 — — WO disclosed
US-20070051944-A1 Organic electroluminescent element MERCK PATENT GMBH (DE) 2007-03-08 — — US disclosed
US-20070051944-A1 Organic electroluminescent element MERCK PATENT GMBH (DE) 2007-03-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070051944-A1 Organic electroluminescent element POU5F1, POU2F1, LEF1 MEN1 2429/4885KMT2A 2877/4885MAPT 1804/4885
US-20110095282-A1 ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING TRIAZINE DERIVATIVES KCNJ2, IKZF2, TERT MEN1 4210/4885KMT2A 1476/4885MAPT 871/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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