Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 8/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8652797 | 0.94 | MEN1 (0.43) | MEN1KMT2APOLBBCHEIDH1 | |
| SCHEMBL28152912 | 0.78 | MEN1 (0.51) | MEN1KMT2APOLBHTT | |
| SCHEMBL8654335 | 0.77 | APP (0.51) | MEN1KMT2APOLBBCHERXRA | |
| SCHEMBL5579323 | 0.77 | KMT2A (0.48) | MEN1KMT2APOLBHTT | |
| SCHEMBL5522119 | 0.76 | LMNA (0.53) | MEN1KMT2ARAB9ASMN1; SMN2BCHE | |
| SCHEMBL12134455 | 0.75 | PTGS2 (0.50) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL11420440 | 0.73 | LTA4H (0.50) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL11420437 | 0.72 | LMNA (0.46) | MEN1KMT2APOLBBCHE | |
| SCHEMBL15472411 | 0.71 | MAOB (0.58) | NPC1RAB9ABCHE | |
| SCHEMBL10828015 | 0.71 | LTA4H (0.50) | MEN1KMT2APOLBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8063249-B1 | Substituted triphenyl butenes | OLEMA PHARMACEUTICALS, INC. (US) | 2011-11-22 | — | — | US | disclosed |