SCHEMBL121349

SCHEMBL121349

O=C(NCCC1CC1)c1cc(Cl)cc(Br)c1NC(=O)c1cc(Br)nn1-c1ncccc1Cl

nearest known ligand 0.61

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
BDKRB1 P46663 10/20 0.39
CHRM4 P08173 3/20 0.39
DHODH Q02127 2/20 0.36
CHRM1 P11229 1/20 0.35
SCD O00767 1/20 0.35
P2RX7 Q99572 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL122340 0.94 BDKRB1 (0.39) BDKRB1CHRM4DHODHCHRM1SCD
SCHEMBL121591 0.92 DHODH (0.40) BDKRB1CHRM4DHODH
SCHEMBL320836 0.92 P2RX7 (0.42) DHODHCHRM1P2RX7
SCHEMBL120762 0.91 BDKRB1 (0.37) BDKRB1CHRM4DHODH
SCHEMBL1958511 0.87 BDKRB1 (0.38) BDKRB1CHRM4DHODH
SCHEMBL1533505 0.85 CHRM4 (0.38) BDKRB1CHRM4DHODH
SCHEMBL17998607 0.84 DHODH (0.37) DHODH
SCHEMBL2138302 0.84 P2RX7 (0.41) CHRM4DHODHCHRM1P2RX7
SCHEMBL15698529 0.84 DHODH (0.37) DHODH
SCHEMBL28517966 0.84 DHODH (0.41) DHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2424370-A2 FOAMABLE PESTICIDE COMPOSITIONS BASF Corporation (US) 2012-03-07 EP claimed
WO-2011025789-A2 FOAMABLE PESTICIDE COMPOSITIONS AND METHODS OF APPLICATION BASF CORPORATION (US) 2011-03-03 WO claimed
US-11576382-B2 Naphthalene isoxazoline compounds for controlling invertebrate pests FMC CORPORATION (US) 2023-02-14 US disclosed
US-11044910-B2 Mesoionic insecticides FMC CORPORATION (US) 2021-06-29 US disclosed
US-20210045388-A1 NAPHTHALENE ISOXAZOLINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS FMC CORPORATION 2021-02-18 US disclosed
US-20200093133-A1 MESOIONIC INSECTICIDES FMC CORPORATION 2020-03-26 US disclosed
EP-2424370-A2 FOAMABLE PESTICIDE COMPOSITIONS BASF Corporation (US) 2012-03-07 EP disclosed
EP-2424347-A1 PESTICIDE COMPOSITIONS AND APPLICATORS BASF Corporation (US) 2012-03-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11044910-B2 Mesoionic insecticides CHRM1, CHRM2, CHRM5 BDKRB1 560/4885CHRM4 8/4885DHODH 2071/4885
US-20200093133-A1 MESOIONIC INSECTICIDES CHRM1, CHRM2, CHRM5 BDKRB1 560/4885CHRM4 8/4885DHODH 2071/4885
US-20210045388-A1 NAPHTHALENE ISOXAZOLINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS RDX, RPS4X, CYP4X1 BDKRB1 312/4885CHRM4 24/4885DHODH 4172/4885
US-11576382-B2 Naphthalene isoxazoline compounds for controlling invertebrate pests RDX, RPS4X, CYP4X1 BDKRB1 312/4885CHRM4 24/4885DHODH 4172/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.