Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 2/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL121591 | 0.92 | DHODH (0.40) | DHODHMALT1CHRM4 | |
| SCHEMBL320836 | 0.92 | P2RX7 (0.42) | P2RX7DHODHMALT1CHRM1KCNH2 | |
| SCHEMBL4155986 | 0.91 | SMO (0.40) | DHODHMALT1DRD4 | |
| SCHEMBL2138881 | 0.91 | P2RX7 (0.39) | P2RX7DHODHMALT1CHRM1CHRM2 | |
| SCHEMBL2083746 | 0.88 | DHODH (0.42) | DHODHMALT1MAPK14CNR2 | |
| SCHEMBL31621733 | 0.88 | DHODH (0.42) | DHODHMALT1CNR2 | |
| SCHEMBL4149532 | 0.88 | CHRM1 (0.40) | CHRM1KCNH2MAPK14CHRM2CHRM4 | |
| SCHEMBL950846 | 0.87 | DHODH (0.44) | P2RX7DHODHMALT1DRD4 | |
| SCHEMBL28425563 | 0.87 | DHODH (0.41) | P2RX7DHODHMALT1DRD4 | |
| SCHEMBL2355865 | 0.87 | DHODH (0.39) | DHODHMALT1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090133318-A1 | Anthranilamide insecticides | E. I. DU PONT DE NEMOURS AND COMPANY | 2009-05-28 | — | — | US | claimed |
| US-20090076092-A1 | METHOD FOR DISRUPTING REPRODUCTIVE PERFORMANCE OF ARTHROPODS | ANNAN ISSAC BILLY | 2009-03-19 | — | — | US | claimed |
| EP-1812421-A2 | ANTHRANILAMIDE INSECTICIDES | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2007-08-01 | — | — | EP | claimed |
| WO-2006055922-A2 | ANTHRANILAMIDE INSECTICIDES | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2006-05-26 | — | — | WO | claimed |
| US-20180168158-A1 | ANTHRANILAMIDE SEED TREATMENT COMPOSITIONS AND METHODS OF USE | PIONEER HI-BRED INTERNATIONAL, INC. (US) | 2018-06-21 | — | — | US | disclosed |
| US-9826737-B2 | Solid formulations of carboxamide arthropodicides | E I DU PONT DE NEMOURS AND COMPANY (US) | 2017-11-28 | — | — | US | disclosed |
| US-20170215419-A1 | ANTHRANILAMIDE SEED TREATMENT COMPOSITIONS AND METHODS OF USE | E I DUPONT DE NEMOURS AND COMPANY | 2017-08-03 | — | — | US | disclosed |
| US-9332756-B2 | Liquid formulations of carboxamide arthropodicides | E I DU PONT DE NEMOURS AND COMPANY (US) | 2016-05-10 | — | — | US | disclosed |
| WO-2016019013-A1 | ANTHRANILAMIDE SEED TREATMENT COMPOSITIONS AND METHODS OF USE | PIONEER HI-BRED INTERNATIONAL, INC. (US) | 2016-02-04 | — | — | WO | disclosed |
| US-8709513-B2 | Liquid formulations of carboxamide arthropodicides | E I DU PONT DE NEMOURS AND COMPANY (DE) | 2014-04-29 | — | — | US | disclosed |
| US-20140005048-A1 | SOLID FORMULATIONS OF CARBOXAMIDE ARTHROPODICIDES | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-01-02 | — | — | US | disclosed |
| EP-2564706-A1 | Anthranilamide insecticides | E. I. du Pont de Nemours and Company (US) | 2013-03-06 | — | — | EP | disclosed |
| EP-1968382-B1 | LIQUID FORMULATIONS OF CARBOXAMIDE ARTHROPODICIDES | DU PONT (US) | 2009-09-16 | — | — | EP | disclosed |
| EP-2094092-A1 | LIQUID FORMULATIONS OF CARBOXAMIDE ARTHROPODICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-09-02 | — | — | EP | disclosed |
| US-20090133318-A1 | Anthranilamide insecticides | E. I. DU PONT DE NEMOURS AND COMPANY | 2009-05-28 | — | — | US | disclosed |
| US-20090076092-A1 | METHOD FOR DISRUPTING REPRODUCTIVE PERFORMANCE OF ARTHROPODS | ANNAN ISSAC BILLY | 2009-03-19 | — | — | US | disclosed |
| US-20080305093-A1 | Liquid Formulations of Carboxamide Arthropodicides | FMC IP TECHNOLOGY GMBH (CH) | 2008-12-11 | — | — | US | disclosed |
| WO-2008069990-A1 | LIQUID FORMULATIONS OF CARBOXAMIDE ARTHROPODICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-06-12 | — | — | WO | disclosed |
| EP-1812421-A2 | ANTHRANILAMIDE INSECTICIDES | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006055922-A2 | ANTHRANILAMIDE INSECTICIDES | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2006-05-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090133318-A1 | Anthranilamide insecticides | C3AR1, C5, C1S | P2RX7 1588/4885DHODH 1809/4885MALT1 1842/4885 |
| US-20090076092-A1 | METHOD FOR DISRUPTING REPRODUCTIVE PERFORMANCE OF ARTHROPODS | NASP, CPS1, CYP11A1 | P2RX7 2217/4885DHODH 313/4885MALT1 4280/4885 |
| US-20080305093-A1 | Liquid Formulations of Carboxamide Arthropodicides | FAAH, C9, FAAH2 | P2RX7 335/4885DHODH 3010/4885MALT1 1766/4885 |
| US-20180168158-A1 | ANTHRANILAMIDE SEED TREATMENT COMPOSITIONS AND METHODS OF USE | AADAC, ABL2, API5 | P2RX7 2813/4885DHODH 1157/4885MALT1 2152/4885 |
| US-20140005048-A1 | SOLID FORMULATIONS OF CARBOXAMIDE ARTHROPODICIDES | FAAH, CNR2, FAAH2 | P2RX7 39/4885DHODH 1975/4885MALT1 2876/4885 |
| US-20170215419-A1 | ANTHRANILAMIDE SEED TREATMENT COMPOSITIONS AND METHODS OF USE | AADAC, ABL2, API5 | P2RX7 2813/4885DHODH 1157/4885MALT1 2152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.