SCHEMBL320836

SCHEMBL320836

O=C(NCC1CC1)c1cc(Cl)cc(Br)c1NC(=O)c1cc(Br)nn1-c1ncccc1Cl

nearest known ligand 0.63

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 2/20 0.42
KCNH2 Q12809 5/20 0.38
DHODH Q02127 2/20 0.37
CAPN1 P07384 1/20 0.36
CACNA1I Q9P0X4 2/20 0.36
CHRM1 P11229 3/20 0.35
MALT1 Q9UDY8 1/20 0.35
NAMPT P43490 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL121349 0.92 BDKRB1 (0.39) P2RX7DHODHCHRM1
SCHEMBL2138302 0.92 P2RX7 (0.41) P2RX7KCNH2DHODHCACNA1ICHRM1
SCHEMBL589854 0.87 CNR2 (0.46) P2RX7KCNH2DHODHCHRM1
SCHEMBL21224545 0.86 P2RX7 (0.38) P2RX7KCNH2CAPN1CHRM1
SCHEMBL122340 0.86 BDKRB1 (0.39) P2RX7DHODHCHRM1
SCHEMBL28503303 0.86 P2RX7 (0.37) P2RX7KCNH2CAPN1CACNA1ICHRM1
SCHEMBL17998607 0.85 DHODH (0.37) DHODHMALT1
SCHEMBL15698529 0.85 DHODH (0.37) DHODHMALT1
SCHEMBL21224583 0.85 P2RX7 (0.37) P2RX7KCNH2CAPN1CACNA1ICHRM1
SCHEMBL28517966 0.85 DHODH (0.41) DHODHMALT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2306831-B1 PESTICIDAL COMPOSITION ISHIHARA SANGYO KAISHA (JP) 2018-03-28 EP claimed
US-8946297-B2 Solid composition for pest control ISHIHARA SANGYO KAISHA, LTD. (JP) 2015-02-03 US claimed
US-8529926-B2 Pesticidal compositions ISHIHARA SANGYO KAISHA, LTD. (JP) 2013-09-10 US claimed
US-20110130427-A1 PESTICIDAL COMPOSITION ISHIHARA SANGYO KAISHA, LTD. (JP) 2011-06-02 US claimed
EP-2306831-A2 PESTICIDAL COMPOSITION ISHIHARA SANGYO KAISHA, LTD. (JP) 2011-04-13 EP claimed
US-20110015237-A1 SOLID COMPOSITION FOR PEST CONTROL ISHIHARA SANGYO KAISHA, LTD. (JP) 2011-01-20 US claimed
US-20100317700-A1 PESTICIDAL COMPOSITIONS ISHIHARA SANGYO KAISHA LTD. (JP) 2010-12-16 US claimed
EP-2255625-A1 SOLID COMPOSITION FOR PEST CONTROL ISHIHARA SANGYO KAISHA, LTD. (JP) 2010-12-01 EP claimed
US-20100028304-A1 PESTICIDAL COMPOSITIONS ISHIHARA SANGYO KAISHA, LTD. (JP) 2010-02-04 US claimed
WO-2010010958-A2 PESTICIDAL COMPOSITION ISHIHARA SANGYO KAISHA, LTD. (JP) 2010-01-28 WO claimed
CN-101557710-A Pesticide composition ISHIHARA SANGYO KAISHA (JP) 2009-10-14 CN claimed
EP-2094087-A1 PESTICIDAL COMPOSITIONS ISHIHARA SANGYO KAISHA, LTD. (JP) 2009-09-02 EP claimed
WO-2008072783-A1 PESTICIDAL COMPOSITIONS ISHIHARA SANGYO KAISHA, LTD. (JP) 2008-06-19 WO claimed
WO-2022138821-A1 DISPERSIBLE CONCENTRATED AGROCHEMICAL FORMULATION 日産化学株式会社 2022-06-30 WO disclosed
US-10299475-B2 Pesticide ISHIHARA SANGYO KAISHA, LTD. (JP) 2019-05-28 US disclosed
US-20180360032-A1 ADDITIVE PACKAGE COMPOSITIONS FOR PESTICIDE SUSPENSION CONCENTRATE FORMULATIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2018-12-20 US disclosed
CN-101557710-A Pesticide composition ISHIHARA SANGYO KAISHA (JP) 2009-10-14 CN disclosed
WO-2009113712-A2 PESTICIDAL COMPOSITIONS ISHIHARA SANGYO KAISHA, LTD. (JP) 2009-09-17 WO disclosed
EP-2094087-A1 PESTICIDAL COMPOSITIONS ISHIHARA SANGYO KAISHA, LTD. (JP) 2009-09-02 EP disclosed
WO-2008072783-A1 PESTICIDAL COMPOSITIONS ISHIHARA SANGYO KAISHA, LTD. (JP) 2008-06-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180360032-A1 ADDITIVE PACKAGE COMPOSITIONS FOR PESTICIDE SUSPENSION CONCENTRATE FORMULATIONS SLC16A7, MPC2, PKD2 P2RX7 1242/4885KCNH2 550/4885DHODH 1374/4885
US-20100317700-A1 PESTICIDAL COMPOSITIONS ACHE, AAAS, AADAC P2RX7 914/4885KCNH2 1151/4885DHODH 1328/4885
US-10299475-B2 Pesticide DDT, ACHE, KCNH1 P2RX7 1487/4885KCNH2 13/4885DHODH 3136/4885
US-20110130427-A1 PESTICIDAL COMPOSITION PHOSPHO1, NAAA, NAPEPLD P2RX7 1516/4885KCNH2 1696/4885DHODH 2539/4885
US-20100028304-A1 PESTICIDAL COMPOSITIONS CNPY3, CNPY2, CRYAA P2RX7 2382/4885KCNH2 84/4885DHODH 3754/4885
US-20110015237-A1 SOLID COMPOSITION FOR PEST CONTROL ANTXR2, STOM, SARAF P2RX7 3004/4885KCNH2 746/4885DHODH 4143/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.