Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.53 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2013094 | 0.98 | SIGMAR1 (0.54) | SIGMAR1CHRM5CHRM3ALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL2009643 | 0.96 | SIGMAR1 (0.53) | SIGMAR1CHRM5CHRM3ALDH1A1POLB | |
| SCHEMBL7111499 | 0.96 | SIGMAR1 (0.53) | SIGMAR1CHRM5CHRM3ALDH1A1POLB | |
| SCHEMBL25162175 | 0.89 | SIGMAR1 (0.47) | SIGMAR1CHRM5CHRM3ALDH1A1POLB | |
| SCHEMBL4086161 | 0.83 | ALDH1A1 (0.54) | SIGMAR1ALDH1A1POLBKCNH2CACNA1I | |
| SCHEMBL12206787 | 0.79 | ALDH1A1 (0.49) | SIGMAR1ALDH1A1POLBKCNH2CACNA1I | |
| SCHEMBL8907384 | 0.79 | ALDH1A1 (0.47) | SIGMAR1ALDH1A1POLBKCNH2CACNA1I | |
| SCHEMBL12428934 | 0.78 | SIGMAR1 (0.44) | SIGMAR1CHRM5CHRM3ALDH1A1POLB | |
| SCHEMBL9232676 | 0.78 | SIGMAR1 (0.46) | SIGMAR1CHRM5CHRM3POLBSMN1; SMN2 | |
| SCHEMBL20946422 | 0.77 | SIGMAR1 (0.63) | SIGMAR1CHRM5CHRM3ALDH1A1CACNA1I |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110280802-A1 | Linkers For Radiopharmaceutical Compounds | BRACCO IMAGING S.P.A. (IT) | 2011-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110280802-A1 | Linkers For Radiopharmaceutical Compounds | VIP, QPCT, NPPA | SIGMAR1 3184/4885CHRM5 450/4885CHRM3 1139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.