Hexoprenaline

Hexoprenaline

SCHEMBL121449

Oc1ccc(C(O)CNCCCCCCNCC(O)c2ccc(O)c(O)c2)cc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 12/20 0.72
MAPT P10636 7/20 0.62
ADRB1 P08588 7/20 0.62
TDP1 Q9NUW8 6/20 0.62
KDM4E B2RXH2 5/20 0.62
DRD2 P14416 5/20 0.62
MEN1 O00255 4/20 0.62
KMT2A Q03164 4/20 0.62
ADRB3 P13945 4/20 0.62
DRD3 P35462 4/20 0.62
MAPK1 P28482 4/20 0.62
DRD1 P21728 4/20 0.62
MTOR P42345 3/20 0.62
TSHR P16473 3/20 0.62
HSD17B10 Q99714 3/20 0.62
CYP3A4 P08684 3/20 0.62
ADORA3 P0DMS8 3/20 0.62
ADRA1D P25100 3/20 0.62
ADRA1A P35348 3/20 0.62
ADRA1B P35368 3/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hexoprenaline SCHEMBL32668781 1.00 ADRB2 (0.72) ADRB2MAPTADRB1TDP1KDM4E
Hexoprenaline SCHEMBL3500862 0.98 ADRB2 (0.70) ADRB2MAPTADRB1TDP1KDM4E
Hexoprenaline SCHEMBL1604446 0.98 ADRB2 (0.70) ADRB2MAPTADRB1TDP1KDM4E
Hexoprenaline SCHEMBL598186 0.94 ADRB2 (0.65) ADRB2MAPTADRB1TDP1KDM4E
SCHEMBL8442887 0.92 ADRB2 (0.63) ADRB2MAPTADRB1TDP1KDM4E
SCHEMBL9768151 0.92 ADRB2 (0.63) ADRB2MAPTADRB1TDP1KDM4E
SCHEMBL9768158 0.92 ADRB2 (0.63) ADRB2MAPTADRB1TDP1KDM4E
SCHEMBL31530706 0.91 ADRB2 (0.68) ADRB2MAPTADRB1TDP1KDM4E
SCHEMBL31530707 0.91 ADRB2 (0.68) ADRB2MAPTADRB1TDP1KDM4E
SCHEMBL13790391 0.91 ADRB2 (0.62) ADRB2MAPTADRB1TDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4190 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4434588-B1 AEROSOL DELIVERY DEVICE PARI PHARMA GMBH (DE) 2026-04-08 EP claimed
US-20250213647-A1 CHEMOKINE RECEPTORS AND ALPHA1 ADRENERGIC RECEPTORS/VASOPRESSIN RECEPTORS 1A HETEROMERS AS DRUG TARGETS FOR DISEASE UNIVERSITY OF SOUTH FLORIDA 2025-07-03 US claimed
WO-2025111482-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS BEXSON BIOMEDICAL, INC. (US) 2025-05-30 WO claimed
US-20250057764-A1 COMPOSITIONS, METHODS AND SYSTEMS FOR AEROSOL DRUG DELIVERY ASTRAZENECA AB (SE) 2025-02-20 US claimed
EP-3711797-B1 AEROSOL DELIVERY DEVICE PARI PHARMA GMBH (DE) 2025-02-12 EP claimed
WO-2025021913-A1 SMALL MOLECULE PROSTAGLANDIN F RECEPTOR ANTAGONISTS FERRING B.V. (NL) 2025-01-30 WO claimed
CN-119233997-A Tetrahedral antibodies 生物分子控股有限责任公司 2024-12-31 CN claimed
US-20240398729-A1 Methods and Compositions for the Treatment of Cytoplasmic Glycogen Storage Disorders DUKE UNIVERSITY (US) 2024-12-05 US claimed
EP-4463485-A2 TETRAHEDRAL ANTIBODIES Biomolecular Holdings LLC (US) 2024-11-20 EP claimed
EP-4452230-A1 COMPOSITIONS, METHODS AND SYSTEMS FOR AEROSOL DRUG DELIVERY Astrazeneca AB (SE) 2024-10-30 EP claimed
US-5215751-A THERAPEUTIC SYSTEM FOR THE RETARDED AND CONTROLLED TRANSDERMAL OR TRANSMUCOUS ADMINISTRATION OF ACTIVE SUBSTANCES (I) LTS LOHMANN THERAPIE SYSTEME GMBH & CO. (DE) 1993-06-01 US claimed
EP-0384267-B1 THERAPEUTIC SYSTEM FOR THE SUSTAINED AND CONTROLLED TRANSDERMAL OR TRANSMUCOSAL DELIVERY OF ACTIVE AGENTS LTS Lohmann Therapie-Systeme GmbH & Co. KG (DE) 1993-05-26 EP claimed
EP-0298984-A1 COMPOSITIONS OF LIPOSOMES AND $g(b) 2?-RECEPTOR ACTIVE SUBSTANCES Aktiebolaget Draco (SE) 1989-01-18 EP claimed
EP-0282537-A1 A NEW SYSTEM FOR ADMINISTRATION OF LIPOSOMES TO MAMMALS Aktiebolaget Draco (SE) 1988-09-21 EP claimed
WO-1988001862-A1 A NEW SYSTEM FOR ADMINISTRATION OF LIPOSOMES TO MAMMALS AKTIEBOLAGET DRACO (SE) 1988-03-24 WO claimed
EP-0260241-A1 A new system for administration of liposomes to mammals Aktiebolaget Draco (SE) 1988-03-16 EP claimed
WO-1987005803-A1 COMPOSITIONS OF LIPOSOMES AND beta2-RECEPTOR ACTIVE SUBSTANCES AKTIEBOLAGET DRACO (SE) 1987-10-08 WO claimed
EP-0022932-B1 COMPOSITION WITH PROLONGED BRONCHOLYTIC AND TOKOLYTIC ACTIVITY, PROCESS FOR PREPARING IT, AND BRONCHOLYTICALLY AND TOKOLYTICALLY ACTIVE AGENT CHEMIE LINZ AKTIENGESELLSCHAFT (AT) 1983-11-02 EP claimed
US-4380534-A WAXES, STEROIDS, ALKALOIDS YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1983-04-19 US claimed
US-4344933-A HEXOPRENALINE COMPOUND WITH A CROSSLINKED STYRENE POLYMER CHEMIE LINZ AKTIENGESELLSCHAFT (AT) 1982-08-17 US claimed