Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 4/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | ICMT | O60725 | 2/20 | 0.34 |
| ▸ | ALB | P02768 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | SELP | P16109 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12145169 | 0.92 | XDH (0.37) | XDHCA14BRD4L3MBTL1 | |
| SCHEMBL12145167 | 0.89 | L3MBTL1 (0.39) | XDHL3MBTL1 | |
| SCHEMBL1371375 | 0.83 | TSHR (0.35) | — | |
| SCHEMBL12145168 | 0.83 | BUB1 (0.36) | XDHL3MBTL1AURKA | |
| SCHEMBL1370716 | 0.82 | HDAC3 (0.40) | — | |
| SCHEMBL7052321 | 0.80 | XDH (0.61) | XDHBRD4GSK3BL3MBTL1AURKA | |
| SCHEMBL5193809 | 0.80 | XDH (0.61) | XDHBRD4GSK3BL3MBTL1AURKA | |
| SCHEMBL2623138 | 0.79 | XDH (0.62) | XDHBRD4GSK3BL3MBTL1AURKA | |
| SCHEMBL1370043 | 0.75 | CA1 (0.49) | XDHL3MBTL1 | |
| SCHEMBL1369226 | 0.74 | CA1 (0.41) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110288106-A1 | ADENINE RECEPTOR LIGANDS | Rheinische Friedrich-Wilhelms-Universitaet Bonn Regina-Pacis-Weg 3 (DE) | 2011-11-24 | — | — | US | disclosed |
| US-20110288106-A1 | ADENINE RECEPTOR LIGANDS | Rheinische Friedrich-Wilhelms-Universitaet Bonn Regina-Pacis-Weg 3 (DE) | 2011-11-24 | — | — | US | disclosed |
| WO-2010000429-A1 | ADENINE RECEPTOR LIGANDS | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2010-01-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110288106-A1 | ADENINE RECEPTOR LIGANDS | ADORA2A, ADORA1, ADORA3 | XDH 408/4885CA14 4876/4885ICMT 3304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.