Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 1.00 |
| ▸ | LMNA | P02545 | 6/20 | 1.00 |
| ▸ | MAPT | P10636 | 6/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 1.00 |
| ▸ | TSHR | P16473 | 5/20 | 1.00 |
| ▸ | POLB | P06746 | 3/20 | 1.00 |
| ▸ | TP53 | P04637 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | APAF1 | O14727 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | GPR3 | P46089 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21788575 | 0.82 | KDM4E (0.68) | KDM4EALDH1A1LMNAMAPTHSD17B10 | |
| SCHEMBL13741622 | 0.79 | KDM4E (0.66) | KDM4EALDH1A1LMNAMAPTHSD17B10 | |
| SCHEMBL12145643 | 0.77 | KDM4E (0.62) | KDM4EALDH1A1LMNAMAPTHSD17B10 | |
| SCHEMBL12759656 | 0.71 | HSD17B10 (0.56) | KDM4EALDH1A1LMNAMAPTHSD17B10 | |
| SCHEMBL12071632 | 0.70 | ALDH1A1 (0.68) | KDM4EALDH1A1LMNAMAPTHSD17B10 | |
| SCHEMBL26667284 | 0.69 | RXFP1 (0.69) | KDM4EALDH1A1LMNAMAPTHSD17B10 | |
| SCHEMBL12145490 | 0.69 | KDM4E (0.63) | KDM4EALDH1A1LMNAMAPTHSD17B10 | |
| SCHEMBL12145479 | 0.68 | KDM4E (0.61) | KDM4EALDH1A1LMNAMAPTHSD17B10 | |
| SCHEMBL21065259 | 0.67 | PDE10A (0.50) | KDM4EALDH1A1LMNAMAPTHSD17B10 | |
| SCHEMBL37035230 | 0.67 | KDM4E (0.61) | KDM4EALDH1A1LMNAMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9169282-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2015-10-27 | — | — | US | disclosed |
| US-9169282-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2015-10-27 | — | — | US | disclosed |
| US-20110284799-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2011-11-24 | — | — | US | disclosed |
| US-20110284799-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2011-11-24 | — | — | US | disclosed |
| WO-2010086089-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2010-08-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110284799-A1 | METAL COMPLEXES | SOD1, AP1M1, AP3M1 | KDM4E 3816/4885ALDH1A1 3721/4885LMNA 4436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.