Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | MLNR | O43193 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12791985 | 0.91 | MEN1 (0.60) | MEN1LMNAMAPTTHRBHTT | |
| SCHEMBL2361662 | 0.87 | MEN1 (0.41) | MEN1LMNAMAPTTHRBHTT | |
| SCHEMBL14457767 | 0.87 | MEN1 (0.41) | MEN1LMNAMAPTTHRBHTT | |
| SCHEMBL29726657 | 0.87 | MEN1 (0.41) | MEN1LMNAMAPTTHRBHTT | |
| SCHEMBL10138057 | 0.87 | MEN1 (0.41) | MEN1LMNAMAPTTHRBHTT | |
| SCHEMBL3859355 | 0.87 | MEN1 (0.41) | MEN1LMNAMAPTTHRBHTT | |
| SCHEMBL559842 | 0.86 | LMNA (0.40) | MEN1LMNAMAPTTHRBHTT | |
| SCHEMBL1405740 | 0.85 | MAPT (0.38) | MEN1LMNAMAPTTHRBHTT | |
| SCHEMBL29773164 | 0.85 | MAPT (0.38) | MEN1LMNAMAPTTHRBHTT | |
| SCHEMBL5268110 | 0.85 | MEN1 (0.39) | MEN1LMNAMAPTTHRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8916137-B2 | Monofunctional carbocyanine dyes for in vivo and in vitro imaging | THE GENERAL HOSPITAL CORPORATION (US) | 2014-12-23 | — | — | US | disclosed |
| US-20110286933-A1 | MONOFUNCTIONAL CARBOCYANINE DYES FOR IN VIVO AND IN VITRO IMAGING | THE GENERAL HOSPITAL CORPORATION (US) | 2011-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110286933-A1 | MONOFUNCTIONAL CARBOCYANINE DYES FOR IN VIVO AND IN VITRO IMAGING | MKI67, HCCS, PYCR1 | MEN1 448/4885LMNA 2640/4885MAPT 4135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.