Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3867446 | 0.91 | TDP1 (0.39) | MEN1KMT2AMAPTLMNATHRB | |
| SCHEMBL3868600 | 0.87 | TDP1 (0.40) | MEN1KMT2AMAPTLMNATHRB | |
| SCHEMBL12146331 | 0.85 | MEN1 (0.56) | MEN1KMT2AMAPTLMNATHRB | |
| SCHEMBL3867937 | 0.84 | HPGD (0.38) | MEN1KMT2AMAPTLMNATHRB | |
| SCHEMBL29726657 | 0.83 | MEN1 (0.41) | MEN1KMT2AMAPTLMNATHRB | |
| SCHEMBL14457767 | 0.83 | MEN1 (0.41) | MEN1KMT2AMAPTLMNATHRB | |
| SCHEMBL3859355 | 0.83 | MEN1 (0.41) | MEN1KMT2AMAPTLMNATHRB | |
| SCHEMBL2361662 | 0.83 | MEN1 (0.41) | MEN1KMT2AMAPTLMNATHRB | |
| SCHEMBL10138057 | 0.83 | MEN1 (0.41) | MEN1KMT2AMAPTLMNATHRB | |
| SCHEMBL559842 | 0.82 | LMNA (0.40) | MEN1KMT2AMAPTLMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0988060-B1 | ACID-LABILE AND ENZYMATICALLY DIVISIBLE DYE COMPOUNDS FOR DIAGNOSIS WITH NEAR INFRARED LIGHT AND FOR THERAPY | DIAGNOSTIKFORSCHUNG INST (DE) | 2007-06-13 | — | — | EP | disclosed |
| US-6534041-B1 | Having little or no fluorescence emission until dye is cleaved from construct at tumor or inflammation target site | INSTITUTE FOR DIAGNOSTIC RESEARCH GMBH OF THE FREE UNIVERSITY OF BERLIN (DE) | 2003-03-18 | — | — | US | disclosed |