SCHEMBL12149302

SCHEMBL12149302

Cc1ccc(-c2ccc3c(c2)C(=C(C#N)C#N)c2ccc4c(c2-3)-c2ccc(-c3ccc(C(F)(F)F)cc3)cc2C4=C(C#N)C#N)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 1/20 0.42
KIF11 P52732 5/20 0.39
PDK2 Q15119 1/20 0.39
KDM1A O60341 1/20 0.38
TDP2 O95551 1/20 0.36
XDH P47989 1/20 0.34
PTPN5 P54829 1/20 0.34
PSEN1 P49768 1/20 0.34
PSEN2 P49810 1/20 0.34
APH1B Q8WW43 1/20 0.34
NCSTN Q92542 1/20 0.34
APH1A Q96BI3 1/20 0.34
PSENEN Q9NZ42 1/20 0.34
GAA P10253 2/20 0.34
MGAM O43451 1/20 0.34
SI P14410 1/20 0.34
MGAM2 Q2M2H8 1/20 0.34
MAPT P10636 2/20 0.33
CTSS P25774 1/20 0.33
CTSK P43235 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15779899 0.93 KIF11 (0.44) ARKIF11PDK2TDP2PSEN1
SCHEMBL12117578 0.91 AR (0.43) ARKIF11PDK2KDM1ATDP2
SCHEMBL12148949 0.91 AR (0.43) ARKIF11PDK2KDM1ATDP2
SCHEMBL20169131 0.88 AR (0.40) ARKIF11PDK2KDM1ATDP2
SCHEMBL10074371 0.86 KIF11 (0.47) ARKIF11PDK2TDP2PSEN1
SCHEMBL12149292 0.85 AR (0.37) ARKIF11PDK2KDM1AXDH
SCHEMBL12148668 0.84 AR (0.38) ARKIF11PDK2KDM1ATDP2
SCHEMBL2756419 0.84 AR (0.39) ARKIF11PDK2KDM1ATDP2
SCHEMBL12149381 0.84 KDM1A (0.43) ARKIF11KDM1AXDHPSEN1
SCHEMBL13374656 0.84 KIF11 (0.45) ARKIF11PDK2TDP2PSEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11575087-B1 Organic electroluminescence device, light emitting device, organic electroluminescence display device and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2023-02-07 US disclosed
US-20110284827-A1 INDENOFLUORENEDIONE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2011-11-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110284827-A1 INDENOFLUORENEDIONE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT HSD17B11, HSD17B2, HSD17B1 AR 134/4885KIF11 1128/4885PDK2 489/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.