SCHEMBL12150671

SCHEMBL12150671

Cc1ccccc1N(c1ccccc1)c1cccc(P(=O)(c2cccc(N(c3ccccc3)c3ccccc3C)n2)c2cccc(N(c3ccccc3)c3ccccc3C)n2)n1

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 1/20 0.35
MEN1 O00255 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33
TSHR P16473 1/20 0.32
APP P05067 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12150670 0.90 CYP1A2 (0.34) MEN1KMT2ATSHR
SCHEMBL185649 0.85 MEN1 (0.36) MEN1HTTKMT2A
SCHEMBL12152003 0.82 SMN1; SMN2 (0.35) MEN1HTTKMT2A
SCHEMBL12150682 0.82 ALDH1A1 (0.38) HDAC6MEN1HTTKMT2AAPP
SCHEMBL2735501 0.77 KCNA5 (0.35) MEN1HTTKMT2A
SCHEMBL12150761 0.77 KCNA5 (0.35) MEN1HTTKMT2A
SCHEMBL12150719 0.76 FBP1 (0.35) MEN1HTTKMT2A
SCHEMBL12150683 0.75 PTGDR2 (0.33)
SCHEMBL12150733 0.75 ALDH1A1 (0.35) MEN1HTTKMT2AAPP
SCHEMBL12150775 0.75 ALDH1A1 (0.35) MEN1HTTKMT2AAPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8722208-B2 Organic electroluminescent device NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2014-05-13 US disclosed
US-8722208-B2 Organic electroluminescent device NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2014-05-13 US disclosed
US-20110284828-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2011-11-24 US disclosed
US-20110284828-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2011-11-24 US disclosed