SCHEMBL185649

SCHEMBL185649

O=P(c1cccc(N(c2ccccc2)c2ccccc2)n1)(c1cccc(N(c2ccccc2)c2ccccc2)n1)c1cccc(N(c2ccccc2)c2ccccc2)n1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
HTT P42858 1/20 0.36
ALDH1A1 P00352 3/20 0.36
TDP1 Q9NUW8 2/20 0.36
POLB P06746 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.32
MAPT P10636 2/20 0.32
KDM4E B2RXH2 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
CRHBP P24387 1/20 0.32
ATM Q13315 1/20 0.32
CRHR2 Q13324 1/20 0.32
TLR9 Q9NR96 1/20 0.32
KCNA5 P22460 1/20 0.31
KCNA3 P22001 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12150682 0.96 ALDH1A1 (0.38) MEN1KMT2AHTTALDH1A1TDP1
SCHEMBL2735501 0.91 KCNA5 (0.35) MEN1KMT2AHTTALDH1A1TDP1
SCHEMBL12150761 0.91 KCNA5 (0.35) MEN1KMT2AHTTALDH1A1TDP1
SCHEMBL12150719 0.90 FBP1 (0.35) MEN1KMT2AHTTALDH1A1TDP1
SCHEMBL12150683 0.89 PTGDR2 (0.33) ALDH1A1CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL12150775 0.89 ALDH1A1 (0.35) MEN1KMT2AHTTALDH1A1TDP1
SCHEMBL12150733 0.89 ALDH1A1 (0.35) MEN1KMT2AHTTALDH1A1TDP1
SCHEMBL12150671 0.85 HDAC6 (0.35) MEN1KMT2AHTT
SCHEMBL12150838 0.84 MAPT (0.33) MEN1KMT2AHTTALDH1A1TDP1
SCHEMBL12150895 0.84 KCNA5 (0.38) MEN1KMT2AHTTALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8722208-B2 Organic electroluminescent device NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2014-05-13 US disclosed
US-8722208-B2 Organic electroluminescent device NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2014-05-13 US disclosed
US-8722208-B2 Organic electroluminescent device NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2014-05-13 US disclosed
EP-2403029-B1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL & SUMIKIN CHEM CO (JP) 2013-11-27 EP disclosed
EP-2403029-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Nippon Steel Chemical Co., Ltd. (JP) 2012-01-04 EP disclosed
EP-2403029-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Nippon Steel Chemical Co., Ltd. (JP) 2012-01-04 EP disclosed
US-20110284828-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2011-11-24 US disclosed
US-20110284828-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2011-11-24 US disclosed
US-20110284828-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2011-11-24 US disclosed