SCHEMBL12152145

SCHEMBL12152145

Cc1cc(-c2nc(-c3ccc(N(C)C)cc3)c(-c3ccc(N(C)C)cc3)[nH]2)c(O)c(C)c1O

nearest known ligand 0.55

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NOX1 Q9Y5S8 4/20 0.55
ALOX5 P09917 3/20 0.49
SMPD3 Q9NY59 3/20 0.44
MGAM O43451 1/20 0.42
PTPN1 P18031 1/20 0.40
TP53 P04637 2/20 0.39
MAPT P10636 2/20 0.39
AURKA O14965 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12152193 0.93 NOX1 (0.55) NOX1ALOX5SMPD3MGAMPTPN1
SCHEMBL12152191 0.88 NOX1 (0.55) NOX1ALOX5SMPD3MGAMPTPN1
SCHEMBL12363832 0.86 SMPD3 (0.45) NOX1ALOX5SMPD3TP53MAPT
SCHEMBL12103631 0.85 NOX1 (0.64) NOX1ALOX5SMPD3PTPN1TP53
SCHEMBL8032578 0.76 NOX1 (0.76) NOX1ALOX5SMPD3PTPN1TP53
SCHEMBL12103613 0.76 NOX1 (0.63) NOX1ALOX5SMPD3PTPN1TP53
SCHEMBL12555646 0.76 NOX1 (0.74) NOX1ALOX5SMPD3MGAMPTPN1
SCHEMBL14003089 0.74 NOX1 (0.60) NOX1ALOX5SMPD3PTPN1TP53
SCHEMBL175592 0.74 SMPD3 (0.75) NOX1ALOX5SMPD3TP53MAPT
SCHEMBL14336058 0.73 NOX1 (0.78) NOX1ALOX5MGAMPTPN1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8999430-B2 Method of manufacturing display element KONICA MINOLTA HOLDINGS, INC. (JP) 2015-04-07 US disclosed
US-8384982-B2 Display element KONICA MINOLTA HOLDINGS, INC. (JP) 2013-02-26 US disclosed
US-8049948-B2 Process for producing electrochemical display element and electrochemical display element KONICA MINOLTA HOLDINGS, INC. (JP) 2011-11-01 US disclosed
US-8014056-B2 Display element and method of driving the same KONICA MINOLTA HOLDINGS, INC. (JP) 2011-09-06 US disclosed
US-20110058244-A1 ELECTROCHROMIC DISPLAY ELEMENT KONICA MINOLTA HOLDINGS, INC. (JP) 2011-03-10 US disclosed
US-20100213813-A1 DISPLAY ELEMENT EDISON INNOVATIONS LLC 2010-08-26 US disclosed
US-20100166946-A1 METHOD OF MANUFACTURING DISPLAY ELEMENT KONICA MINOLTA HOLDINGS, INC. (JP) 2010-07-01 US disclosed
US-20100134864-A1 PROCESS FOR PRODUCING ELECTROCHEMICAL DISPLAY ELEMENT AND ELECTROCHEMICAL DISPLAY ELEMENT KONICA MINOLTA HOLDINGS ,INC. (JP) 2010-06-03 US disclosed
US-20100091353-A1 DISPLAY ELEMENT AND METHOD OF DRIVING THE SAME KONICA MINOLTA HOLDINGS, INC. (JP) 2010-04-15 US disclosed
US-7619803-B2 Electrochromic display element and full-color electrochromic display element KONICA MINOLTA HOLDINGS, INC. (JP) 2009-11-17 US disclosed
US-20090027757-A1 ELECTROCHROMIC DISPLAY ELEMENT AND FULL-COLOR ELECTROCHROMIC DISPLAY ELEMENT KONICA MINOLTA HOLDINGS, INC. (JP) 2009-01-29 US disclosed