SCHEMBL12152191

SCHEMBL12152191

Cc1cc(C)c(O)c(-c2nc(-c3ccc(N(C)C)cc3)c(-c3ccc(N(C)C)cc3)[nH]2)c1

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NOX1 Q9Y5S8 4/20 0.55
ALOX5 P09917 2/20 0.49
SMPD3 Q9NY59 3/20 0.47
MGAM O43451 1/20 0.42
AURKA O14965 1/20 0.41
CSNK1D P48730 1/20 0.40
CSNK1E P49674 1/20 0.40
MAPK14 Q16539 1/20 0.40
PTPN1 P18031 1/20 0.40
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
ALDH1A1 P00352 1/20 0.39
GLA P06280 1/20 0.39
GAA P10253 1/20 0.39
HPGD P15428 1/20 0.39
KMT2A Q03164 1/20 0.39
TP53 P04637 1/20 0.39
MAPT P10636 1/20 0.39
TEK Q02763 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12152145 0.88 NOX1 (0.55) NOX1ALOX5SMPD3MGAMAURKA
SCHEMBL12152193 0.85 NOX1 (0.55) NOX1ALOX5SMPD3MGAMAURKA
SCHEMBL12103631 0.85 NOX1 (0.64) NOX1ALOX5SMPD3AURKACSNK1D
SCHEMBL12152241 0.80 ALOX5 (0.51) NOX1ALOX5SMPD3MGAMCSNK1D
SCHEMBL8032578 0.76 NOX1 (0.76) NOX1ALOX5SMPD3CSNK1DCSNK1E
SCHEMBL12103613 0.76 NOX1 (0.63) NOX1ALOX5SMPD3AURKAMAPK14
SCHEMBL12555646 0.76 NOX1 (0.74) NOX1ALOX5SMPD3MGAMMAPK14
SCHEMBL12363832 0.75 SMPD3 (0.45) NOX1ALOX5SMPD3MEN1KMT2A
SCHEMBL175592 0.74 SMPD3 (0.75) NOX1ALOX5SMPD3KDM4EMEN1
SCHEMBL14003089 0.74 NOX1 (0.60) NOX1ALOX5SMPD3PTPN1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8999430-B2 Method of manufacturing display element KONICA MINOLTA HOLDINGS, INC. (JP) 2015-04-07 US disclosed
US-8384982-B2 Display element KONICA MINOLTA HOLDINGS, INC. (JP) 2013-02-26 US disclosed
US-8049948-B2 Process for producing electrochemical display element and electrochemical display element KONICA MINOLTA HOLDINGS, INC. (JP) 2011-11-01 US disclosed
US-8014056-B2 Display element and method of driving the same KONICA MINOLTA HOLDINGS, INC. (JP) 2011-09-06 US disclosed
US-8004742-B2 Electrochromic display device KONICA MINOLTA HOLDINGS, INC. (JP) 2011-08-23 US disclosed
US-20110058244-A1 ELECTROCHROMIC DISPLAY ELEMENT KONICA MINOLTA HOLDINGS, INC. (JP) 2011-03-10 US disclosed
US-20100213813-A1 DISPLAY ELEMENT EDISON INNOVATIONS LLC 2010-08-26 US disclosed
US-20100166946-A1 METHOD OF MANUFACTURING DISPLAY ELEMENT KONICA MINOLTA HOLDINGS, INC. (JP) 2010-07-01 US disclosed
US-20100134864-A1 PROCESS FOR PRODUCING ELECTROCHEMICAL DISPLAY ELEMENT AND ELECTROCHEMICAL DISPLAY ELEMENT KONICA MINOLTA HOLDINGS ,INC. (JP) 2010-06-03 US disclosed
US-20100091353-A1 DISPLAY ELEMENT AND METHOD OF DRIVING THE SAME KONICA MINOLTA HOLDINGS, INC. (JP) 2010-04-15 US disclosed
US-20090316249-A1 ELECTROCHROMIC DISPLAY DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2009-12-24 US disclosed
US-7619803-B2 Electrochromic display element and full-color electrochromic display element KONICA MINOLTA HOLDINGS, INC. (JP) 2009-11-17 US disclosed
US-20090027757-A1 ELECTROCHROMIC DISPLAY ELEMENT AND FULL-COLOR ELECTROCHROMIC DISPLAY ELEMENT KONICA MINOLTA HOLDINGS, INC. (JP) 2009-01-29 US disclosed