Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.76 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | TP53 | P04637 | 4/20 | 0.59 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.59 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.59 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.59 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.59 |
| ▸ | RAF1 | P04049 | 2/20 | 0.59 |
| ▸ | BRAF | P15056 | 2/20 | 0.59 |
| ▸ | GCGR | P47871 | 2/20 | 0.59 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.58 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | CIT | O14578 | 1/20 | 0.58 |
| ▸ | GAK | O14976 | 1/20 | 0.58 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.58 |
| ▸ | BRD4 | O60885 | 1/20 | 0.58 |
| ▸ | GMNN | O75496 | 1/20 | 0.58 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8010209 | 0.87 | NOX1 (0.76) | NOX1ALOX5MAPTTP53MAPK14 | |
| SCHEMBL1071183 | 0.86 | NOX1 (1.00) | NOX1ALOX5MAPTTP53MAPK14 | |
| SCHEMBL5622957 | 0.85 | ALOX5 (0.87) | NOX1ALOX5MAPTMAPK14MAPK13 | |
| SCHEMBL6468252 | 0.85 | NOX1 (0.76) | NOX1ALOX5MAPTTP53MAPK14 | |
| SCHEMBL8797410 | 0.83 | NOX1 (0.72) | NOX1ALOX5MAPTTP53MAPK14 | |
| SCHEMBL12103631 | 0.83 | NOX1 (0.64) | NOX1ALOX5MAPTTP53MAPK14 | |
| SCHEMBL6467424 | 0.82 | NOX1 (0.72) | NOX1ALOX5MAPTTP53MAPK14 | |
| SCHEMBL12103613 | 0.82 | NOX1 (0.63) | NOX1ALOX5MAPTTP53MAPK14 | |
| SCHEMBL14336058 | 0.82 | NOX1 (0.78) | NOX1ALOX5MAPTTP53MAPK14 | |
| SCHEMBL9619859 | 0.81 | MAPK13 (0.85) | NOX1ALOX5MAPTTP53MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347139-A2 | Imidazole leuco dye composition containing 4'-hydroxyacetanilide diagnostic kit and method using same | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1989-12-20 | — | — | EP | claimed |
| US-4089747-A | OXIDATION OF DYE-PROVIDING MATERIALS, A SULFONYL HYDRAZONE AND A COUPLER OR A TRIARYLIMIDAZOLE | EASTMAN KODAK COMPANY (US) | 1978-05-16 | — | — | US | claimed |
| EP-0603954-B1 | Immunoassay using a 4-hydroxy or 4-alkoxyarylacetamide as stabilizer | JOHNSON & JOHNSON CLIN DIAG (US) | 2000-03-08 | — | — | EP | disclosed |
| EP-0603953-B1 | Use of 4' of 5'-hydroxy and 4'- or 5'-alkoxy-substituted electron transfer agents in compositions, elements, test kits and analytical methods | JOHNSON & JOHNSON CLIN DIAG (US) | 1999-02-17 | — | — | EP | disclosed |
| US-5700826-A | SENSITIZATION OF CANCER CELLS TO DRUG | ONTOGEN CORPORATION (US) | 1997-12-23 | — | — | US | disclosed |
| EP-0812829-A1 | Substituted imidazoles as modulators of multi-drug resistance | ONTOGEN CORPORATION (US) | 1997-12-17 | — | — | EP | disclosed |
| EP-0431682-B1 | Buffered wash composition, insolubilizing composition, test kits and method of use | EASTMAN KODAK CO (US) | 1995-02-01 | — | — | EP | disclosed |
| US-5372931-A | Use of 4'-hydroxy- and 4'-alkoxy-substituted electron transfer agents in compositions, elements, test kits and analytical methods | EASTMAN KODAK COMPANY (US) | 1994-12-13 | — | — | US | disclosed |
| US-5372932-A | Peroxidase-labeled immunoreactant; stabiliztion with a 4-hydroxy or 4-alkoxyarylacetamide | EASTMAN KODAK COMPANY (US) | 1994-12-13 | — | — | US | disclosed |
| EP-0308236-B1 | Dye-providing composition, diagnostic test kit and their use in method for ligand determination using peroxidase labeled-receptor | EASTMAN KODAK CO (US) | 1994-11-23 | — | — | EP | disclosed |
| US-5366864-A | Buffered wash composition, insolubilizing composition, test kits and method of use | EASTMAN KODAK COMPANY (US) | 1994-11-22 | — | — | US | disclosed |
| EP-0603953-A1 | Use of 4' of 5'-hydroxy and 4'- or 5'-alkoxy-substituted electron transfer agents in compositions, elements, test kits and analytical methods | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1994-06-29 | — | — | EP | disclosed |
| EP-0603954-A2 | Analytical element and immunoassay using a 4-hydroxy or 4-alkoxyarylacetamide as stabilizer | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1994-06-29 | — | — | EP | disclosed |
| US-5176999-A | BUFFERED WASH COMPOSITION, INSOLUBILIZING COMPOSITION, TEST KITS AND METHOD OF USE | EASTMAN KODAK COMPANY (US) | 1993-01-05 | — | — | US | disclosed |
| US-5047318-A | Detection Of Grampositive Bacteria | EASTMAN KODAK COMPANY (US) | 1991-09-10 | — | — | US | disclosed |
| US-5024935-A | Determination of human chorionic gonadotropin | EASTMAN KODAK COMPANY (US) | 1991-06-18 | — | — | US | disclosed |
| EP-0431682-A2 | Buffered wash composition, insolubilizing composition, test kits and method of use | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1991-06-12 | — | — | EP | disclosed |
| EP-0347139-A2 | Imidazole leuco dye composition containing 4'-hydroxyacetanilide diagnostic kit and method using same | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1989-12-20 | — | — | EP | disclosed |
| EP-0308236-A2 | Dye-providing composition, diagnostic test kit and their use in method for ligand determination using peroxidase labeled-receptor | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1989-03-22 | — | — | EP | disclosed |
| US-4089747-A | OXIDATION OF DYE-PROVIDING MATERIALS, A SULFONYL HYDRAZONE AND A COUPLER OR A TRIARYLIMIDAZOLE | EASTMAN KODAK COMPANY (US) | 1978-05-16 | — | — | US | disclosed |