Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 7/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9414550 | 0.82 | PAOX (0.64) | PAOXALDH1A1MAOAMAOBADRA1A | |
| SCHEMBL16727725 | 0.80 | PAOX (0.79) | PAOXALDH1A1ADRA1AKDM4EMAPK1 | |
| SCHEMBL7922962 | 0.79 | PAOX (0.60) | PAOXALDH1A1ADRA1ALMNASLC15A2 | |
| SCHEMBL12974337 | 0.77 | PAOX (0.46) | PAOXMAOAMAOBHDAC6 | |
| SCHEMBL12292278 | 0.77 | PAOX (0.58) | PAOXALDH1A1MAOAMAOBADRA1A | |
| SCHEMBL12292305 | 0.77 | PAOX (0.58) | PAOXALDH1A1MAOAMAOBADRA1A | |
| SCHEMBL7885797 | 0.76 | PAOX (0.56) | PAOXALDH1A1MAOAMAOBADRA1A | |
| SCHEMBL12409524 | 0.75 | PAOX (0.44) | PAOXMAOAMAOBHDAC6 | |
| SCHEMBL12292303 | 0.75 | PAOX (0.44) | PAOXMAOAMAOBHDAC6 | |
| SCHEMBL12155256 | 0.75 | PAOX (0.44) | PAOXMAOAMAOBHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9371350-B2 | Trehalose derivatives and pharmaceutical compositions for treating neurodegenerative diseases | POSTECH FOUNDATION (KR) | 2016-06-21 | — | — | US | disclosed |
| US-20150025035-A1 | INOSITOL AND TREHALOSE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING NEURODEGENERATIVE DISEASES COMPRISING THE SAME | POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) | 2015-01-22 | — | — | US | disclosed |
| US-8048996-B2 | Molecular transporters based on sugar and its analogues and processes for the preparation thereof | POSTECH FOUNDATION (KR) | 2011-11-01 | — | — | US | disclosed |
| US-20110224423-A1 | INOSITOL AND TREHALOSE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING NEURODEGENERATIVE DISEASES COMPRISING THE SAME | POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) | 2011-09-15 | — | — | US | disclosed |
| US-7973084-B2 | High permeability through plasma membrane, nuclear membrane and blood-brain barrier; for delivering doxorubicin and paclitaxel to target cells; gene therapy | POSTECH ACADEMY-INDUSTRIAL FOUNDATION (KR) | 2011-07-05 | — | — | US | disclosed |
| US-20100330608-A1 | MOLECULAR TRANSPORTERS BASED ON SUGAR AND ITS ANALOGUES AND PROCESSES FOR THE PREPARATION THEREOF | POSTECH FOUNDATION (KR) | 2010-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110224423-A1 | INOSITOL AND TREHALOSE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING NEURODEGENERATIVE DISEASES COMPRISING THE SAME | HTT, TREH, ITPA | PAOX 3568/4885ALDH1A1 2541/4885MAOA 2060/4885 |
| US-20100330608-A1 | MOLECULAR TRANSPORTERS BASED ON SUGAR AND ITS ANALOGUES AND PROCESSES FOR THE PREPARATION THEREOF | SLC2A1, SLC2A8, SLC2A2 | PAOX 1538/4885ALDH1A1 3245/4885MAOA 4440/4885 |
| US-20150025035-A1 | INOSITOL AND TREHALOSE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING NEURODEGENERATIVE DISEASES COMPRISING THE SAME | HTT, TREH, ITPA | PAOX 3568/4885ALDH1A1 2541/4885MAOA 2060/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.