Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 6/20 | 0.52 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.51 |
| ▸ | EGFR | P00533 | 2/20 | 0.51 |
| ▸ | KDR | P35968 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 5/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12157483 | 0.93 | MAPT (0.58) | MAPTRAB9AKDM4ENPC1NPSR1 | |
| SCHEMBL2588882 | 0.92 | MAPT (0.58) | MAPTRAB9AKDM4ENPC1NPSR1 | |
| SCHEMBL5259792 | 0.85 | MAPT (0.58) | MAPTRAB9AKDM4ENPC1NPSR1 | |
| SCHEMBL2590596 | 0.84 | MAPT (0.61) | MAPTRAB9AKDM4ENPC1NPSR1 | |
| SCHEMBL12157498 | 0.84 | MAPT (0.61) | MAPTRAB9AKDM4ENPC1NPSR1 | |
| SCHEMBL15958900 | 0.84 | MAPT (0.64) | MAPTRAB9AKDM4ENPC1NPSR1 | |
| SCHEMBL2595246 | 0.82 | MAPT (0.46) | MAPTRAB9AKDM4ENPC1NPSR1 | |
| SCHEMBL12157485 | 0.82 | MAPT (0.56) | MAPTRAB9AKDM4ENPC1NPSR1 | |
| SCHEMBL2587158 | 0.80 | MAPT (0.50) | MAPTRAB9AKDM4ENPC1NPSR1 | |
| SCHEMBL2578128 | 0.80 | LMNA (0.48) | MAPTRAB9AKDM4ENPC1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110268896-A1 | ORGANIC FLUORESCENT COMPOSITIONS | HONEYWELL INTERNATIONAL INC. (US) | 2011-11-03 | — | — | US | disclosed |
| US-20090114355-A1 | ORGANIC FLUORESCENT COMPOSITIONS | HONEYWELL INTERNATIONAL INC. (US) | 2009-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090114355-A1 | ORGANIC FLUORESCENT COMPOSITIONS | PFAS, FUS, ACR | MAPT 27/4885RAB9A 2507/4885KDM4E 3212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.