Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.34 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | WNT1 | P04628 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20678135 | 0.93 | GLA (0.43) | GLAPLA2G10PLA2G5CACNA1HAPEX1 | |
| SCHEMBL15938241 | 0.93 | GLA (0.43) | GLAPLA2G10PLA2G5CACNA1HAPEX1 | |
| SCHEMBL15831754 | 0.88 | HSD17B10 (0.37) | PLA2G10PLA2G5CACNA1HSMN1; SMN2CHRM2 | |
| SCHEMBL12158290 | 0.87 | SMN1; SMN2 (0.43) | PLA2G10PLA2G5CACNA1HSMN1; SMN2SIGMAR1 | |
| SCHEMBL16656261 | 0.87 | GLA (0.39) | GLAPLA2G10PLA2G5CACNA1HAPEX1 | |
| SCHEMBL12156742 | 0.84 | GLA (0.50) | GLAAPEX1SMN1; SMN2CYP1A2MAPK1 | |
| SCHEMBL20678137 | 0.84 | SIGMAR1 (0.40) | GLAPLA2G10PLA2G5CACNA1HSMN1; SMN2 | |
| SCHEMBL17119745 | 0.84 | HSD17B10 (0.36) | GLAPLA2G10PLA2G5CACNA1HSMN1; SMN2 | |
| SCHEMBL20678139 | 0.84 | HSD17B10 (0.36) | GLAPLA2G10PLA2G5CACNA1HSMN1; SMN2 | |
| Bromide SCHEMBL5132382 | 0.81 | CYP1A2 (0.47) | GLAPLA2G10PLA2G5CACNA1HSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8911710-B2 | Intravascular contrast agents | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2014-12-16 | — | — | US | disclosed |
| US-20110268663-A1 | INTRAVASCULAR CONTRAST AGENTS | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2011-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110268663-A1 | INTRAVASCULAR CONTRAST AGENTS | C3AR1, CD47, C5AR2 | GLA 2952/4885PLA2G10 1099/4885PLA2G5 800/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.