Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.34 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.34 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | WNT1 | P04628 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20678135 | 0.94 | GLA (0.43) | GLAPLA2G10PLA2G5CACNA1HSMN1; SMN2 | |
| SCHEMBL15938241 | 0.94 | GLA (0.43) | GLAPLA2G10PLA2G5CACNA1HSMN1; SMN2 | |
| SCHEMBL16656254 | 0.92 | CYP1A2 (0.45) | PLA2G10PLA2G5CACNA1HPAOXSMN1; SMN2 | |
| SCHEMBL16656264 | 0.90 | PAOX (0.44) | PLA2G10PLA2G5CACNA1HPAOXSMN1; SMN2 | |
| SCHEMBL10016097 | 0.88 | HSD17B10 (0.38) | PLA2G10PLA2G5CACNA1HSMN1; SMN2CHRM2 | |
| SCHEMBL14680626 | 0.87 | PLA2G10 (0.38) | PLA2G10PLA2G5CACNA1HSMN1; SMN2CYP1A2 | |
| SCHEMBL12158286 | 0.87 | GLA (0.38) | GLAPLA2G10PLA2G5CACNA1HSMN1; SMN2 | |
| SCHEMBL20678137 | 0.86 | SIGMAR1 (0.40) | GLAPLA2G10PLA2G5CACNA1HSMN1; SMN2 | |
| SCHEMBL20678139 | 0.85 | HSD17B10 (0.36) | GLAPLA2G10PLA2G5CACNA1HSMN1; SMN2 | |
| SCHEMBL17119745 | 0.85 | HSD17B10 (0.36) | GLAPLA2G10PLA2G5CACNA1HSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9012604-B2 | Triazanonane derivatives or pharmaceutically acceptable salt thereof for enhanced fluorine-18 labeling | Snur & DB Foundation (KR) | 2015-04-21 | — | — | US | disclosed |