Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 3/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | VDR | P11473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12106786 | 0.85 | ITGB3 (0.47) | ITGB3ITGA2B | |
| SCHEMBL12160456 | 0.85 | ITGB3 (0.47) | ITGB3ITGA2B | |
| SCHEMBL12103606 | 0.84 | MAPK1 (0.41) | THRATHRB | |
| SCHEMBL27810440 | 0.84 | MAPK1 (0.41) | THRATHRB | |
| Hydrochloric Acid SCHEMBL1295995 | 0.83 | MAPK1 (0.40) | THRATHRB | |
| Hydrochloric Acid SCHEMBL1295997 | 0.83 | MAPK1 (0.40) | THRATHRB | |
| SCHEMBL1296483 | 0.81 | GPR119 (0.44) | ACACBGPR119 | |
| SCHEMBL1296480 | 0.81 | GPR119 (0.44) | ACACBGPR119 | |
| SCHEMBL27830881 | 0.78 | ITGB3 (0.35) | ITGB3ITGA2BTHRATHRBHRH3 | |
| SCHEMBL2372432 | 0.78 | GPR119 (0.43) | ACACBGPR119HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2383270-A1 | Piperidine GPCR agonists | Prosidion Limited (GB) | 2011-11-02 | — | — | EP | disclosed |