Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 18/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 18/20 | 0.47 |
| ▸ | ITGAV | P06756 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12106786 | 1.00 | ITGB3 (0.47) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL12106892 | 0.91 | ITGB3 (0.48) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL12160457 | 0.89 | GPR119 (0.47) | ITGB3ITGA2B | |
| SCHEMBL12160406 | 0.89 | GPR119 (0.47) | ITGB3ITGA2B | |
| SCHEMBL12160423 | 0.89 | GPR119 (0.47) | ITGB3ITGA2B | |
| SCHEMBL13534979 | 0.87 | ITGB3 (0.45) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL12160488 | 0.86 | ITGB3 (0.53) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL1841876 | 0.85 | GPR119 (0.42) | — | |
| SCHEMBL12160436 | 0.85 | ITGB3 (0.47) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL12160383 | 0.85 | ACACB (0.35) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2383270-A1 | Piperidine GPCR agonists | Prosidion Limited (GB) | 2011-11-02 | — | — | EP | disclosed |